| Author | : Wenwei Yu |
| Publisher | : CRC Press |
| Total Pages | : 485 |
| Release | : 2012-12-03 |
| Genre | : Medical |
| ISBN | : 1439871744 |
Therapeutic Engineering (TE) is a cutting-edge domain in today's era of medical technology research. Through engineering algorithms that provide technological solutions, it aims to elevate the quality of life of disabled individuals. Advances in Therapeutic Engineering describes various therapeutic processes and mechanisms currently applied to the
| Author | : William R Strohl |
| Publisher | : Elsevier |
| Total Pages | : 697 |
| Release | : 2012-10-16 |
| Genre | : Medical |
| ISBN | : 1908818093 |
The field of antibody engineering has become a vital and integral part of making new, improved next generation therapeutic monoclonal antibodies, of which there are currently more than 300 in clinical trials across several therapeutic areas. Therapeutic antibody engineering examines all aspects of engineering monoclonal antibodies and analyses the effect that various genetic engineering approaches will have on future candidates. Chapters in the first part of the book provide an introduction to monoclonal antibodies, their discovery and development and the fundamental technologies used in their production. Following chapters cover a number of specific issues relating to different aspects of antibody engineering, including variable chain engineering, targets and mechanisms of action, classes of antibody and the use of antibody fragments, among many other topics. The last part of the book examines development issues, the interaction of human IgGs with non-human systems, and cell line development, before a conclusion looking at future issues affecting the field of therapeutic antibody engineering. - Goes beyond the standard engineering issues covered by most books and delves into structure-function relationships - Integration of knowledge across all areas of antibody engineering, development, and marketing - Discusses how current and future genetic engineering of cell lines will pave the way for much higher productivity
| Author | : Wenwei Yu |
| Publisher | : CRC Press |
| Total Pages | : 499 |
| Release | : 2012-12-03 |
| Genre | : Medical |
| ISBN | : 1439871736 |
Therapeutic Engineering (TE) is a cutting-edge domain in today’s era of medical technology research. Through engineering algorithms that provide technological solutions, it aims to elevate the quality of life of disabled individuals. Advances in Therapeutic Engineering describes various therapeutic processes and mechanisms currently applied to the field of healthcare in a range of areas, including mobility, communications, hearing, vision, and mental health and cognition. The book explores research and advances in the areas of hand-eye coordination, motor function, the biomechanics of lower limbs, and treatment of spinal diseases and neural plasticity. It discusses electrical stimulation methodologies for improving human gait. It also examines prosthetic devices and assistive technology, induction heater-based treatment, and inclusive user modelling and simulation. Additional chapters cover automated asthma detection using clinico–spirometric information, computer-aided diagnostic modules for malaria screening, and various data mining techniques that have been developed and successfully implemented in healthcare management. The contributors also examine semantic interoperability issues in e-health systems and clinical decision support systems (CDSSs) Ranging from prosthetics to sensory substitution and medical robotics, the book will prove enlightening to researchers and practitioners in a host of disciplines who want to understand the recent advances achieved globally in the field of therapeutic engineering.
| Author | : Huimin Zhao |
| Publisher | : John Wiley & Sons |
| Total Pages | : 41 |
| Release | : 2021-08-23 |
| Genre | : Science |
| ISBN | : 3527344705 |
A one-stop reference that reviews protein design strategies to applications in industrial and medical biotechnology Protein Engineering: Tools and Applications is a comprehensive resource that offers a systematic and comprehensive review of the most recent advances in the field, and contains detailed information on the methodologies and strategies behind these approaches. The authors—noted experts on the topic—explore the distinctive advantages and disadvantages of the presented methodologies and strategies in a targeted and focused manner that allows for the adaptation and implementation of the strategies for new applications. The book contains information on the directed evolution, rational design, and semi-rational design of proteins and offers a review of the most recent applications in industrial and medical biotechnology. This important book: Covers technologies and methodologies used in protein engineering Includes the strategies behind the approaches, designed to help with the adaptation and implementation of these strategies for new applications Offers a comprehensive and thorough treatment of protein engineering from primary strategies to applications in industrial and medical biotechnology Presents cutting edge advances in the continuously evolving field of protein engineering Written for students and professionals of bioengineering, biotechnology, biochemistry, Protein Engineering: Tools and Applications offers an essential resource to the design strategies in protein engineering and reviews recent applications.
| Author | : Waqar Ahmed |
| Publisher | : Academic Press |
| Total Pages | : 422 |
| Release | : 2020-03-21 |
| Genre | : Technology & Engineering |
| ISBN | : 012822603X |
Advances in Medical and Surgical Engineering integrates the knowledge and experience of experts from academia and practicing surgeons working with patients. The cutting-edge progress in medical technology applications is making the traditional line between engineering and medical science ever thinner. This is an excellent resource for biomedical engineers working in industry and academia on developing medical technologies. It covers challenges in the application of technology in the clinic with views from an editorial team that is highly experienced in engineering, biomaterials, surgical practice, biomedical science and technology, and that has a proven track record of publishing applied biomedical science and technology. For medical practitioners, this book covers advances in technology in their domain. For students, this book identifies the opportunities of research based on the reviews of utilization of current technologies. The content in this book can also be of interest to policymakers, research funding agencies, and libraries, that are contributing to development of medical technologies. - Covers circulatory support, aortic valve implantation and microvascular antestmosis - Explores arthroplasty of both the knee and the shoulder - Includes tribology of materials, laser treatment and machining of biomaterial
| Author | : J. Donald Capra |
| Publisher | : Karger Publishers |
| Total Pages | : 218 |
| Release | : 1997 |
| Genre | : Immunoglobulins |
| ISBN | : 9783805563567 |
The last decade has witnessed remarkable developments in antibody research and its therapeutic applications. With the methods of molecular biology it is now possible to manipulate the specificities and activities of antibody molecules to generate an almost limitless array of structures for both basic investigations and the clinical setting. The contributions to this volume cover all three domains of the antibody: the variable regions, the relatively neglected but crucial hinge, and the constant region. These studies provide critical structural and functional information about antibodies, while also pointing the way to the construction of molecules with enhanced or even novel properties. Bringing together major experts on antibody engineering, this book is highly recommended to faculty, postdoctoral fellows and graduate students in molecular biology, microbiology, immunology, cancer research and genetics.
| Author | : Valentina Emilia Balas |
| Publisher | : Academic Press |
| Total Pages | : 382 |
| Release | : 2019-06-14 |
| Genre | : Science |
| ISBN | : 0128173572 |
Internet of Things in Biomedical Engineering presents the most current research in Internet of Things (IoT) applications for clinical patient monitoring and treatment. The book takes a systems-level approach for both human-factors and the technical aspects of networking, databases and privacy. Sections delve into the latest advances and cutting-edge technologies, starting with an overview of the Internet of Things and biomedical engineering, as well as a focus on 'daily life.' Contributors from various experts then discuss 'computer assisted anthropology,' CLOUDFALL, and image guided surgery, as well as bio-informatics and data mining. This comprehensive coverage of the industry and technology is a perfect resource for students and researchers interested in the topic. - Presents recent advances in IoT for biomedical engineering, covering biometrics, bioinformatics, artificial intelligence, computer vision and various network applications - Discusses big data and data mining in healthcare and other IoT based biomedical data analysis - Includes discussions on a variety of IoT applications and medical information systems - Includes case studies and applications, as well as examples on how to automate data analysis with Perl R in IoT
| Author | : Stephen H. Tsang |
| Publisher | : Springer |
| Total Pages | : 180 |
| Release | : 2017-11-11 |
| Genre | : Science |
| ISBN | : 3319639048 |
This book presents descriptive overviews of gene editing strategies across multiple species while also offering in-depth insight on complex cases of application in the field of tissue engineering and regenerative medicine. Chapters feature contributions from leaders in stem cell therapy and biology, providing a comprehensive view of the application of gene therapy in numerous fields with an emphasis on ophthalmology, stem cells, and agriculture. The book also highlights recent major technological advances, including ZFN, TALEN, and CRISPR. Precision Medicine, CRISPR, and Genome Engineering is part of the highly successful Advances in Experimental Medicine and Biology series. It is an indispensable resource for researchers and students in genetics as well as clinicians.
| Author | : Gil Gonçalves |
| Publisher | : Springer |
| Total Pages | : 0 |
| Release | : 2018-06-12 |
| Genre | : Technology & Engineering |
| ISBN | : 9783319898773 |
This book presents a systematic overview of the most relevant nanomaterials and their respective intrinsic properties that have been highly explored by the scientific community and pharmaceutical companies in several different modalities for cancer therapy and bioimaging. The chapters explore the synergistic effects provided by the different nanostructured materials and highlight the main in vitro and in vivo therapeutic achievements on cancer. This work also provides relevant discussion about the recent progresses and future challenges that nanotechnology faces on the conception of more efficient nanoformulations against primary tumors, circulating cancer cells and metastases.
