This document represents a joint effort between two action networks of the Global Agenda: (i) Closing the Efficiency Gap and (ii) the Global Network on Silvopastoral Systems. A framework for evaluating natural resource use efficiency is applied to a variety of silvopastoral production models to determine productivity and their socio-economic and environmental benefits. It presents an overview of SPS, their main characteristics and advantages regarding production and benefits for the environment and climate, and their contribution to the SDGs, describing the results of ten case studies of adoption of SPS in diverse contexts in Colombia, Mexico, and Argentina, with a focus on land productivity, meat and milk production, and economic performance at the farm level. Based on the findings, a number of policy recommendations are made with a view to scaling-up and promoting SPS in Latin America and other regions.