| Author | : Axel Schmidt |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 241 |
| Release | : 2006-03-30 |
| Genre | : Medical |
| ISBN | : 3764373393 |
-SARS has received much attention and coverage by the media and has a high impact on the public making this a hot research topic for scientists. -
| Author | : Stuart G. Siddell |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 424 |
| Release | : 2013-06-29 |
| Genre | : Medical |
| ISBN | : 1489915311 |
Coronaviruses were recognized as a group of enveloped, RNA viruses in 1968 and accepted by the International Committee on the Taxonomy of Viruses as a separate family, the Coronaviridae, in 1975. By 1978, it had become evident that the coronavirus genomic RNA was infectious (i. e. , positive strand), and by 1983, at least the framework of the coronavirus replication strategy had been per ceived. Subsequently, with the application of recombinant DNA techniques, there have been remarkable advances in our understanding of the molecular biology of coronaviruses, and a mass of structural data concerning coronavirus genomes, mRNAs, and pro teins now exists. More recently, attention has been focused on the role of essential and accessory gene products in the coronavirus replication cyde and a molecular analysis of the structure-function relation ships of coronavirus proteins. Nevertheless, there are still large gaps in our knowledge, for instance, in areas such as the genesis of coronavirus subgenomic mRNAs or the function of the coronavirus RNA-dependent RNA polymerase. The diseases caused by coronaviruses have been known for much longer than the agents themselves. Possibly the first coronavirus-related disease to be recorded was feline infectious peritonitis, as early as 1912. The diseases associ ated with infectious bronchitis virus, transmissible gastroenteritis virus, and murine hepatitis virus were all well known before 1950.
| Author | : Moulay Mustapha Ennaji |
| Publisher | : Academic Press |
| Total Pages | : 389 |
| Release | : 2019-09-14 |
| Genre | : Science |
| ISBN | : 0128149671 |
Emerging and Reemerging Viral Pathogens: Applied Virology Approaches Related to Human, Animal and Environmental Pathogens, Volume Two presents new research information on viruses and their impact on the scientific community. It provides a reference book on certain viruses in humans, animals and vegetal, along with a comprehensive discussion on interspecies interactions. The book then looks at the drug, vaccine and bioinformatical strategies that can be used against these viruses, giving the reader a clear understanding of transmission. The book's end goal is to create awareness that the appearance of newly transmissible pathogens is a global risk that requires shared/adoptable policies for prevention and control. - Covers most emerging viral disease in humans, animals and plants - Provides the most advanced tools and techniques in molecular virology and the modeling of viruses - Creates awareness that the appearance of new transmissible pathogens is a global risk - Highlights the need to adopt shared policies for the prevention and control of infectious diseases
| Author | : Vladimir Uversky |
| Publisher | : John Wiley & Sons |
| Total Pages | : 532 |
| Release | : 2012-02-07 |
| Genre | : Science |
| ISBN | : 0470618310 |
This book provides up-to-date information on experimental and computational characterization of the structural and functional properties of viral proteins, which are widely involved in regulatory and signaling processes. With chapters by leading research groups, it features current information on the structural and functional roles of intrinsic disorders in viral proteomes. It systematically addresses the measles, HIV, influenza, potato virus, forest virus, bovine virus, hepatitis, and rotavirus as well as viral genomics. After analyzing the unique features of each class of viral proteins, future directions for research and disease management are presented.
| Author | : Satya Prakash Gupta |
| Publisher | : Academic Press |
| Total Pages | : 518 |
| Release | : 2017-07-03 |
| Genre | : Science |
| ISBN | : 0128096829 |
Viral Proteases and Their Inhibitors provides a thorough examination of viral proteases from their molecular components, to therapeutic applications. As information on three dimensional structures and biological functions of these viral proteases become known, unexpected protein folds and unique mechanisms of proteolysis are realized. This book investigates how this facilitates the design and development of potent antiviral agents used against life-threatening viruses. Users will find descriptions of each virus that detail the structure and function of viral proteases, discuss the design and development of inhibitors, and analyze the structure-activity relationships of inhibitors. This book is ideal biochemists, virologists and those working on antiviral agents. Provides comprehensive, state-of-the-art coverage of virus infections, the virus lifecycle, and mechanisms of protease inhibition Analyzes structure-activity relationships of inhibitors of each viral protease Presents an in-depth view of the structure and function of viral proteases
| Author | : Joel Sussman |
| Publisher | : World Scientific |
| Total Pages | : 597 |
| Release | : 2008 |
| Genre | : Science |
| ISBN | : 9812772049 |
Ranging from policy issues related to funding and goals, through high-throughput procedures for protein production, this text presents an overview of structural proteomics via a multidisciplinary approach involving molecular biology.
| Author | : Moulay Mustapha Ennaji |
| Publisher | : Academic Press |
| Total Pages | : 1170 |
| Release | : 2019-09-27 |
| Genre | : Science |
| ISBN | : 0128194014 |
Emerging and Reemerging Viral Pathogens: Fundamental and Basic Virology Aspects of Human, Animal and Plant Pathogens, Volume One presents new research information on viruses and their impact on the scientific community. It provides a reference book on certain viruses in humans, animals and vegetal, along with a comprehensive discussion on interspecies interactions. The book then looks at the drug, vaccine and bioinformatical strategies that can be used against these viruses, giving the reader a clear understanding of transmission. The book's end goal is to create awareness that the appearance of newly transmissible pathogens is a global risk that requires shared/adoptable policies for prevention and control. - Covers most emerging viral disease in humans, animals and plants - Provides the most advanced tools and techniques in molecular virology and the modeling of viruses - Creates awareness that the appearance of new transmissible pathogens is a global risk - Highlights the need to adopt shared policies for the prevention and control of infectious diseases
| Author | : Mithun Rudrapal |
| Publisher | : Bentham Science Publishers |
| Total Pages | : 254 |
| Release | : 2023-11-05 |
| Genre | : Medical |
| ISBN | : 9815049526 |
This comprehensive reference explores medicinal plants, phytomedicines, and traditional herbal remedies as potential sources for the prevention and treatment of COVID-19. It features 9 chapters authored and edited by renowned experts. The book specifically highlights the promising drug discovery opportunities grounded in bioactive compounds from medicinal plants and herbal medicines, offering insights into combatting SARS-CoV-2 infections and respiratory complications. Key Highlights: Drug Discovery Potential: Explores the vast potential of medicinal plants, phytomedicine, and traditional remedies against COVID-19, shedding light on groundbreaking drug discovery avenues. Cutting-Edge Insights: Provides up-to-date insights into the use of medicinal plants, herbal drugs, and traditional medicines in the fight against COVID-19. Natural Immune Boosters: Details the use of indigenous herbs, spices, functional foods, and herbal drugs for boosting immunity and preventing SARS-CoV-2 infections. Drug Repurposing: Highlights innovative drug repurposing strategies using phytomedicine-derived bioactive compounds and phytochemical databases for COVID-19 drug development. Additional features of the book include a reader-friendly introduction to each topic and a list of references for advanced readers. This timely reference is an informative resource for a broad range of readers interested in strategies to control COVID-19, including postgraduate researchers, and pharmaceutical R&D experts. It also serves as a handbook for professionals in clinical and herbal medicine.
| Author | : Stanley Perlman |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 623 |
| Release | : 2007-05-01 |
| Genre | : Medical |
| ISBN | : 0387330127 |
This volume is based on the 10th International Nidovirus Symposium: Towards Control of SARS and other Nidovirus Diseases. The volume includes articles by all of the major contributors to this burgeoning area of research which summarize the work presented at the meeting. This represents the only comprehensive book to cover this field in the last five years.
