Dermal Exposure

Dermal Exposure
Author: World Health Organization
Publisher: Environmental Health Criteria
Total Pages: 0
Release: 2014
Genre: Medical
ISBN: 9789241572422

"IPCS, International Programme on Chemical Safety."

Wildlife Toxicity Assessments for Chemicals of Military Concern

Wildlife Toxicity Assessments for Chemicals of Military Concern
Author: Marc Williams
Publisher: Elsevier
Total Pages: 725
Release: 2015-05-21
Genre: Science
ISBN: 0128004800

Wildlife Toxicity Assessments for Chemicals of Military Concern is a compendium of chemical-specific toxicity information with discussions on the rationale and development of Wildlife Toxicity Reference Values (TRVs) intended for use on terrestrial wildlife for risk assessment applications. Substances covered include military-related chemicals including explosives, propellants, pesticides and metals. Wildlife Toxicity Assessments for Chemicals of Military Concern is a much-needed resource designed to meet the needs of those seeking toxicological information for ecological risk assessment purposes. Each chapter targets a specific chemical and considers the current knowledge of the toxicological impacts of chemicals to terrestrial wildlife including mammalian, avian, amphibian and reptilian species. - Provides detailed information on how Wildlife Toxicity Values (TRVs) for military chemicals of concern are derived and evaluated. - Covers wildlife toxicity assessments of explosives, metals and environmental chemicals. - Compiles relevant information on the environmental effects of chemicals on wildlife in relation to public and environmental health.

Toxicologic Assessment of Jet-Propulsion Fuel 8

Toxicologic Assessment of Jet-Propulsion Fuel 8
Author: National Research Council
Publisher: National Academies Press
Total Pages: 229
Release: 2003-02-14
Genre: Nature
ISBN: 0309168708

This report provides a critical review of toxicologic, epidemiologic, and other relevant data on jet-propulsion fuel 8, a type of fuel in wide use by the U.S. Department of Defense (DOD), and an evaluation of the scientific basis of DOD's interim permissible exposure level of 350 mg/m3

Dermal Absorption and Toxicity Assessment

Dermal Absorption and Toxicity Assessment
Author: Michael S. Roberts
Publisher: CRC Press
Total Pages: 704
Release: 2007-12-14
Genre: Medical
ISBN: 0849375924

The source Dermal Absorption and Toxicity Assessment supplies a state-of-the-art overview of the dermal absorption process, and is divided into six well organized sections. Written by internationally recognized experts in the field, this Second Edition is a complete revised and updated text, covering the wide range of methods used to assess skin ab

An Introduction to Interdisciplinary Toxicology

An Introduction to Interdisciplinary Toxicology
Author: Carey N. Pope
Publisher: Academic Press
Total Pages: 644
Release: 2020-02-21
Genre: Technology & Engineering
ISBN: 0128136022

An Introduction to Interdisciplinary Toxicology: From Molecules to Man integrates the various aspects of toxicology, from "simpleā€ molecular systems, to complex human communities, with expertise from a spectrum of interacting disciplines. Chapters are written by specialists within a given subject, such as a chemical engineer, nutritional scientist, or a microbiologist, so subjects are clearly explained and discussed within the toxicology context. Many chapters are comparative across species so that students in ecotoxicology learn mammalian toxicology and vice versa. Specific citations, further reading, study questions, and other learning features are also included. The book allows students to concurrently learn concepts in both biomedical and environmental toxicology fields, thus better equipping them for the many career opportunities toxicology provides. This book will also be useful to those wishing to reference how disciplines interact within the broad field of toxicology.

Contaminated Water Supplies at Camp Lejeune

Contaminated Water Supplies at Camp Lejeune
Author: National Research Council
Publisher: National Academies Press
Total Pages: 338
Release: 2009-09-06
Genre: Medical
ISBN: 0309136997

In the early 1980s, two water-supply systems on the Marine Corps Base Camp Lejeune in North Carolina were found to be contaminated with the industrial solvents trichloroethylene (TCE) and perchloroethylene (PCE). The water systems were supplied by the Tarawa Terrace and Hadnot Point watertreatment plants, which served enlisted-family housing, barracks for unmarried service personnel, base administrative offices, schools, and recreational areas. The Hadnot Point water system also served the base hospital and an industrial area and supplied water to housing on the Holcomb Boulevard water system (full-time until 1972 and periodically thereafter). This book examines what is known about the contamination of the water supplies at Camp Lejeune and whether the contamination can be linked to any adverse health outcomes in former residents and workers at the base.

Exposure Assessment for Epidemiology and Hazard Control

Exposure Assessment for Epidemiology and Hazard Control
Author: Acgih
Publisher: CRC Press
Total Pages: 344
Release: 1990-11-21
Genre: Science
ISBN: 9780873711975

What agents should be measured? How should measurement be performed and what averaging time should be used for the measurement? What sampling strategy should be employed to characterize exposures across individuals, locations, and time? What durations of exposure should be characterized? What statistical descriptors should be used to relate exposure to effect? Exposure Assessment for Epidemiology and Hazard Control examines various approaches to answering these and other important questions. Other topics discussed include the measurement of current exposures (e.g., vapors, gases, aerosols, and complex mixtures); the application of toxicological relationships, including biological markers and sample models; an epidemiological evaluation of exposure-effect relationships, including new methods for effect evaluation and models for population exposure estimates; and strategies for exposure assessment, such as biological sampling interpretation through toxicokinetic processes. This important new volume contains essential information for industrial hygienists, epidemiologists, occupational health physicians, toxicologists, and immunologists.

Physiologically Based Pharmacokinetic (PBPK) Modeling

Physiologically Based Pharmacokinetic (PBPK) Modeling
Author: Jeffrey W. Fisher
Publisher: Academic Press
Total Pages: 348
Release: 2020-05-20
Genre: Medical
ISBN: 0128196823

Physiologically Based Pharmacokinetic (PBPK) Modeling: Methods and Applications in Toxicology and Risk Assessment presents foundational principles, advanced techniques and applications of PBPK modeling. Contributions from experts in PBPK modeling cover topics such as pharmacokinetic principles, classical physiological models, the application of physiological models for dose-response and risk assessment, the use of in vitro information, and in silico methods. With end-of-chapter exercises that allow readers to practice and learn the skills associated with PBPK modeling, dose-response, and its applications to safety and risk assessments, this book is a foundational resource that provides practical coverage of PBPK modeling for graduate students, academics, researchers, and more. - Provides end-of-chapter exercises to teach hands-on computational tools used in toxicology - Supplies computer code and explanations and includes examples of applied models used in regulatory toxicology and research - Authored by expert editors and contributors who are among the best PBPK modelers in the world