Colloidal Dispersions

Colloidal Dispersions
Author: William Bailey Russel
Publisher: Cambridge University Press
Total Pages: 548
Release: 1991
Genre: Mathematics
ISBN: 9780521426008

This book covers the physical side of colloidal science from the individual forces acting between particles smaller than a micrometer that are suspended in a liquid, through the resulting equilibrium and dynamic properties. A variety of internal forces both attractive and repulsive act in conjunction with Brownian motion and the balance between them all decides the phase behaviour. On top of this various external fields, such as gravity or electromagnetic fields, diffusion and non-Newtonian rheology produce complex effects, each of which is of important scientific and technological interest. The authors aim to impart a sound, quantitative understanding based on fundamental theory and experiments with well-characterised model systems. This broad grasp of the fundamentals lends insight and helps to develop the intuitive sense needed to isolate essential features of the technological problems and design critical experiments. The main prerequisites for understanding the book are basic fluid mechanics, statistical mechanics and electromagnetism, though self contained reviews of each subject are provided at appropriate points. Some facility with differential equations is also necessary. Exercises are included at the end of each chapter, making the work suitable as a textbook for graduate courses in chemical engineering or applied mathematics. It will also be useful as a reference for individuals in academia or industry undertaking research in colloid science.

Rheology of Dispersions

Rheology of Dispersions
Author: Tharwat F. Tadros
Publisher: John Wiley & Sons
Total Pages: 218
Release: 2011-07-18
Genre: Science
ISBN: 3527632395

A dispersion is a system of unmixable phases in which one phase is continuous and at least one is finely distributed. Examples are found in many industrial applications, including emulsions, suspensions, foams, and geld. The control of their flow characteristics - rheology - is essential in their preparation, long-term physical stability and application. Filling the need for a practical, up-to-date book connecting the stability/instability of the dispersion to its rheological behavior, this title aids in understanding the principles of rheology and the techniques that can be applied. From the contents: * General Introduction * Interparticle Interactions and Their Combination * Principles of Viscoelastic Behavior * Rheology of Suspensions * Rheology of Emulsions * Rheology of Modifiers, Thickeners, and Gels * Use of Rheological Measurements for Assessment and Prediction of the Long-Term Physical Stability of Formulations (Creaming and Sedimentation)

Dispersions

Dispersions
Author: Erik Kissa
Publisher: CRC Press
Total Pages: 728
Release: 1999-06-15
Genre: Science
ISBN: 9780824719944

Explaining principles essential for the interpretation of data and understanding the real meaning of the result, this work describes carious methods and techniques used to characterize dispersions and measure their physical and chemical properties. It describes a variety of dispersions containing particles ranging from submicron sizes to aggregates and from hard particles to polymer latices.

Pharmaceutical Solid Dispersion Technology

Pharmaceutical Solid Dispersion Technology
Author: Muhammad J. Habib
Publisher: CRC Press
Total Pages: 114
Release: 2000-10-05
Genre: Medical
ISBN: 9781566768139

There has not, until now, been a single up-to-date volume to provide those in drug R&D with practical information on all aspects of solid dispersion technology for drugs. This forthcoming volume finally provides such a guide and reference. The unified presentation by a team of specialists in this field is designed for practical application. Theoretical concepts are covered for a fuller understanding of current techniques. All significant recent developments are included.

Amorphous Solid Dispersions

Amorphous Solid Dispersions
Author: Navnit Shah
Publisher: Springer
Total Pages: 702
Release: 2014-11-21
Genre: Medical
ISBN: 1493915983

This volume offers a comprehensive guide on the theory and practice of amorphous solid dispersions (ASD) for handling challenges associated with poorly soluble drugs. In twenty-three inclusive chapters, the book examines thermodynamics and kinetics of the amorphous state and amorphous solid dispersions, ASD technologies, excipients for stabilizing amorphous solid dispersions such as polymers, and ASD manufacturing technologies, including spray drying, hot melt extrusion, fluid bed layering and solvent-controlled micro-precipitation technology (MBP). Each technology is illustrated by specific case studies. In addition, dedicated sections cover analytical tools and technologies for characterization of amorphous solid dispersions, the prediction of long-term stability, and the development of suitable dissolution methods and regulatory aspects. The book also highlights future technologies on the horizon, such as supercritical fluid processing, mesoporous silica, KinetiSol®, and the use of non-salt-forming organic acids and amino acids for the stabilization of amorphous systems. Amorphous Solid Dispersions: Theory and Practice is a valuable reference to pharmaceutical scientists interested in developing bioavailable and therapeutically effective formulations of poorly soluble molecules in order to advance these technologies and develop better medicines for the future.

Solid - Liquid Dispersions

Solid - Liquid Dispersions
Author: Bohuslav Dobias
Publisher: CRC Press
Total Pages: 586
Release: 1999-03-04
Genre: Science
ISBN: 9780824700140

Reviews a range of fundamental concepts, recent developments and practical applications in dispersion theory, along with relevant insights from colloidal and interfacial science. The text contains new work on the stabilization of solid-liquid dispersions. It focuses on topics as varied as electrostatics, hydrodynamics and rheology.

Pharmaceutical Amorphous Solid Dispersions

Pharmaceutical Amorphous Solid Dispersions
Author: Ann Newman
Publisher: John Wiley & Sons
Total Pages: 502
Release: 2015-03-09
Genre: Science
ISBN: 1118455207

Providing a roadmap from early to late stages of drug development, this book overviews amorphous solid dispersion technology – a leading platform to deliver poorly water soluble drugs, a major hurdle in today’s pharmaceutical industry. • Helps readers understand amorphous solid dispersions and apply techniques to particular pharmaceutical systems • Covers physical and chemical properties, screening, scale-up, formulation, drug product manufacture, intellectual property, and regulatory considerations • Has an appendix with structure and property information for polymers commonly used in drug development and with marketed drugs developed using the amorphous sold dispersion approach • Addresses global regulatory issues including USA regulations, ICH guidelines, and patent concerns around the world

Polymer Dispersions and Their Industrial Applications

Polymer Dispersions and Their Industrial Applications
Author: Dieter Urban
Publisher: Wiley-VCH
Total Pages: 436
Release: 2002
Genre: Science
ISBN:

Aqueous polymer dispersions are environmentally friendly and therefore they have replaced in many applications polymers dissolved in organic solvents. This substitution process is still ongoing. This book discusses the world of aqueous polymer dispersions from the viewpoint of how they are applied. For a better understanding it starts with a general description of the synthesis of polymer dispersions and their characterization. The following chapters are dedicated to a wide variety of applications, including history, modern processes, and typical formulations and performance. The selection and the usage of a polymer dispersion are not uniform around the world because of historical and regional differences of the technical developments and marketing demands. Leading scientists from industry contributed to this book ensuring that practical issues are emphasized.

Characterization of Liquids, Dispersions, Emulsions, and Porous Materials Using Ultrasound

Characterization of Liquids, Dispersions, Emulsions, and Porous Materials Using Ultrasound
Author: Andrei S. Dukhin
Publisher: Elsevier
Total Pages: 592
Release: 2017-08-08
Genre: Technology & Engineering
ISBN: 0444639071

Characterization of Liquids, Dispersions, Emulsions and Porous Materials Using Ultrasound, Third Edition, presents a scientific background for novel methods of characterizing homogeneous and heterogeneous liquids (dispersions, emulsions, and gels) as well as porous materials. Homogeneous liquids are characterized in rheological terms, whereas particle-size distribution and zeta potential are parameters of heterogeneous liquids. For porous materials, porosity, pore size, and zeta potential are output characteristics. These methods are based on ultrasound, which opens an opportunity for simplifying the sample preparation by eliminating dilution. This in turn, makes measurements faster, easier, precise, suitable for accurate quality control, PAT, and formulation of complex systems. This book provides theoretical background of acoustics, rheology, colloid science, electrochemistry, and other relevant scientific fields, describing principles of existing instrumentation and, in particular, commercially available instruments. Finally, the book features an extensive list of existing applications. - Presents a theoretical multi-disciplinary background of several new ultrasound analytical techniques in one place - Validates the theoretical basis of several new analytical techniques - Compares the efficiency and applications of various ultrasound techniques - Lists many ultrasound applications in colloid chemistry - Contains an extensive bibliography on this multidisciplinary topic