Emerging Trends in Applications and Infrastructures for Computational Biology, Bioinformatics, and Systems Biology

by Hamid R Arabnia
Emerging Trends in Applications and Infrastructures for Computational Biology, Bioinformatics, and Systems Biology
Author: Hamid R Arabnia
Publisher: Morgan Kaufmann
Total Pages: 594
Release: 2016-03-25
Genre: Computers
ISBN: 0128042591
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Emerging Trends in Applications and Infrastructures for Computational Biology, Bioinformatics, and Systems Biology: Systems and Applications covers the latest trends in the field with special emphasis on their applications. The first part covers the major areas of computational biology, development and application of data-analytical and theoretical methods, mathematical modeling, and computational simulation techniques for the study of biological and behavioral systems. The second part covers bioinformatics, an interdisciplinary field concerned with methods for storing, retrieving, organizing, and analyzing biological data. The book also explores the software tools used to generate useful biological knowledge. The third part, on systems biology, explores how to obtain, integrate, and analyze complex datasets from multiple experimental sources using interdisciplinary tools and techniques, with the final section focusing on big data and the collection of datasets so large and complex that it becomes difficult to process using conventional database management systems or traditional data processing applications. Explores all the latest advances in this fast-developing field from an applied perspective Provides the only coherent and comprehensive treatment of the subject available Covers the algorithm development, software design, and database applications that have been developed to foster research

Emerging Trends in Computational Biology, Bioinformatics, and Systems Biology

by Hamid R Arabnia
Emerging Trends in Computational Biology, Bioinformatics, and Systems Biology
Author: Hamid R Arabnia
Publisher: Morgan Kaufmann
Total Pages: 670
Release: 2015-08-11
Genre: Computers
ISBN: 0128026464
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Emerging Trends in Computational Biology, Bioinformatics, and Systems Biology discusses the latest developments in all aspects of computational biology, bioinformatics, and systems biology and the application of data-analytics and algorithms, mathematical modeling, and simu- lation techniques. • Discusses the development and application of data-analytical and theoretical methods, mathematical modeling, and computational simulation techniques to the study of biological and behavioral systems, including applications in cancer research, computational intelligence and drug design, high-performance computing, and biology, as well as cloud and grid computing for the storage and access of big data sets. • Presents a systematic approach for storing, retrieving, organizing, and analyzing biological data using software tools with applications to general principles of DNA/RNA structure, bioinformatics and applications, genomes, protein structure, and modeling and classification, as well as microarray analysis. • Provides a systems biology perspective, including general guidelines and techniques for obtaining, integrating, and analyzing complex data sets from multiple experimental sources using computational tools and software. Topics covered include phenomics, genomics, epigenomics/epigenetics, metabolomics, cell cycle and checkpoint control, and systems biology and vaccination research. • Explains how to effectively harness the power of Big Data tools when data sets are so large and complex that it is difficult to process them using conventional database management systems or traditional data processing applications. - Discusses the development and application of data-analytical and theoretical methods, mathematical modeling and computational simulation techniques to the study of biological and behavioral systems. - Presents a systematic approach for storing, retrieving, organizing and analyzing biological data using software tools with applications. - Provides a systems biology perspective including general guidelines and techniques for obtaining, integrating and analyzing complex data sets from multiple experimental sources using computational tools and software.

Systems Biology Modelling and Analysis

by Elisabetta De Maria
Systems Biology Modelling and Analysis
Author: Elisabetta De Maria
Publisher: John Wiley & Sons
Total Pages: 468
Release: 2022-11-18
Genre: Science
ISBN: 1119716586
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Systems Biology Modelling and Analysis Describes important modelling and computational methods for systems biology research to enable practitioners to select and use the most suitable technique Systems Biology Modelling and Analysis provides an overview of state-of-the-art techniques and introduces related tools and practices to formalize models and automate reasoning for systems biology. The authors present and compare the main formal methods used in systems biology for modelling biological networks, including discussion of their advantages, drawbacks, and main applications. Each chapter includes an intuitive presentation of the specific formalism, a brief history of the formalism and of its applications in systems biology, a formal description of the formalism and its variants, at least one realistic case study, some applications of formal techniques to validate and make deep analysis of models encoded with the formalism, and a discussion on the kind of biological systems for which the formalism is suited, along with concrete ideas on its possible evolution. Edited by a highly qualified expert with significant experience in the field, some of the methods and techniques covered in Systems Biology Modelling and Analysis include: Petri nets, an important tool for studying different aspects of biological systems, ranging from simple signaling pathways to metabolic networks and beyond Pathway Logic, a formal, rule-based system and interactive viewer for developing executable models of cellular processes Boolean networks, a mathematical model which has been widely used for decades in the context of biological regulation networks Answer Set Programming (ASP), which has proven to be a strong logic programming paradigm to deal with the inherent complexity of biological models For systems biologists, biochemists, bioinformaticians, molecular biologists, pharmacologists, and computer scientists, Systems Biology Modelling and Analysis is a comprehensive all-in-one resource to understand and harness the field’s current models and techniques while also preparing for their potential developments in coming years with the help of the author’s expert insight.

Omics Applications for Systems Biology

by Wan Mohd Aizat
Omics Applications for Systems Biology
Author: Wan Mohd Aizat
Publisher: Springer
Total Pages: 111
Release: 2018-10-31
Genre: Science
ISBN: 3319987585
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This book explains omics at the most basic level, including how this new concept can be properly utilized in molecular and systems biology research. Most reviews and books on this topic have mainly focused on the technicalities and complexity of each omics’ platform, impeding readers to wholly understand its fundamentals and applications. This book tackles such gap and will be most beneficial to novice in this area, university students and even researchers. Basic workflow and practical guidance in each omics are also described, such that scientists can properly design their experimentation effectively. Furthermore, how each omics platform has been conducted in our institute (INBIOSIS) is also detailed, a comprehensive example on this topic to further enhance readers’ understanding. The contributors of each chapter have utilized the platforms in various manner within their own research and beyond. The contributors have also been interactively integrated and combined these different omics approaches in their research, being able to systematically write each chapter with the conscious knowledge of other inter-relating topics of omics. The potential readers and audience of this book can come from undergraduate and postgraduate students who wish to extend their comprehension in the topics of molecular biology and big data analysis using omics platforms. Furthermore, researchers and scientists whom may have expertise in basic molecular biology can extend their experimentation using the omics technologies and workflow outlined in this book, benefiting their research in the long run.

Hybrid Artificial Intelligent Systems

by Hilde Pérez García
Hybrid Artificial Intelligent Systems
Author: Hilde Pérez García
Publisher: Springer Nature
Total Pages: 782
Release: 2019-08-26
Genre: Computers
ISBN: 3030298590
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This volume constitutes the refereed proceedings of the 14th International Conference on Hybrid Artificial Intelligent Systems, HAIS 2019, held in León, Spain, in September 2019. The 64 full papers published in this volume were carefully reviewed and selected from 134 submissions. They are organized in the following topical sections: data mining, knowledge discovery and big data; bio-inspired models and evolutionary computation; learning algorithms; visual analysis and advanced data processing techniques; data mining applications; and hybrid intelligent applications.

Digital Transformation of Identity in the Age of Artificial Intelligence

by Kazuhiko Shibuya
Digital Transformation of Identity in the Age of Artificial Intelligence
Author: Kazuhiko Shibuya
Publisher: Springer Nature
Total Pages: 295
Release: 2020-02-19
Genre: Mathematics
ISBN: 9811522480
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This book examines the digital transformation of identity in the age of artificial intelligence. It articulates the nature of identity of human beings, based on cutting-edge knowledge in the field of AI and big-data sciences, and discusses identity by drawing on comprehensive investigations in digital social sciences and exploring wider disciplines related to philosophy, ethics, sociology, STS, computer sciences, engineering, and medical sciences. Reviewing contemporary conditions proliferated by advanced technological trends and unveiling social mechanisms of human identity, this book appeals to undergraduate and graduate students as well as academic researchers.

Protein Interaction Networks

by Rossen Donev
Protein Interaction Networks
Author: Rossen Donev
Publisher: Academic Press
Total Pages: 354
Release: 2022-07-21
Genre: Science
ISBN: 0323992323
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Protein Interaction Networks, Volume 131 in the Advances in Protein Chemistry and Structural Biology series, highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors. - Provides the authority and expertise of leading contributors from an international board of authors - Presents the latest release in the Advances in Protein Chemistry and Structural Biology series - Includes the latest information on protein design and structure