| Author | : Muin J. Khoury |
| Publisher | : Monographs in Epidemiology and |
| Total Pages | : 394 |
| Release | : 1993 |
| Genre | : Medical |
| ISBN | : 0195052889 |
This text integrates the principles, methods and approaches of epidemiology and genetics in the study of disease aetiology. The authors define the central theme of genetic epidemiology as the study of the role of genetic factors and their interaction with environmental factors in the occurrence of disease in populations.
| Author | : Muin J. Khoury |
| Publisher | : Oxford University Press |
| Total Pages | : 701 |
| Release | : 2010-01-20 |
| Genre | : Medical |
| ISBN | : 0195398440 |
The first edition of Human Genome Epidemiology, published in 2004, discussed how the epidemiologic approach provides an important scientific foundation for studying the continuum from gene discovery to the development, applications and evaluation of human genome information in improving health and preventing disease. Since that time, advances in human genomics have continued to occur at a breathtaking pace.With contributions from leaders in the field from around the world, this new edition is a fully updated look at the ways in which genetic factors in common diseases are studied. Methodologic developments in collection, analysis and synthesis of data, as well as issues surrounding specific applications of human genomic information for medicine and public health are all discussed. In addition, the book focuses on practical applications of human genome variation in clinical practice and disease prevention. Students, clinicians, public health professionals and policy makers will find the book a useful tool for understanding the rapidly evolving methods of the discovery and use of genetic information in medicine and public health in the 21st century.
| Author | : Paul A. Schulte |
| Publisher | : Academic Press |
| Total Pages | : 609 |
| Release | : 2012-12-02 |
| Genre | : Medical |
| ISBN | : 0323138578 |
This book will serve as a primer for both laboratory and field scientists who are shaping the emerging field of molecular epidemiology. Molecular epidemiology utilizes the same paradigm as traditional epidemiology but uses biological markers to identify exposure, disease or susceptibility. Schulte and Perera present the epidemiologic methods pertinent to biological markers. The book is also designed to enumerate the considerations necessary for valid field research and provide a resource on the salient and subtle features of biological indicators.
| Author | : Robert C. Elston |
| Publisher | : John Wiley & Sons |
| Total Pages | : 384 |
| Release | : 2008-11-20 |
| Genre | : Medical |
| ISBN | : 0470024917 |
Anyone who attempts to read genetics or epidemiology research literature needs to understand the essentials of biostatistics. This book, a revised new edition of the successful Essentials of Biostatistics has been written to provide such an understanding to those who have little or no statistical background and who need to keep abreast of new findings in this fast moving field. Unlike many other elementary books on biostatistics, the main focus of this book is to explain basic concepts needed to understand statistical procedures. This Book: Surveys basic statistical methods used in the genetics and epidemiology literature, including maximum likelihood and least squares. Introduces methods, such as permutation testing and bootstrapping, that are becoming more widely used in both genetic and epidemiological research. Is illustrated throughout with simple examples to clarify the statistical methodology. Explains Bayes’ theorem pictorially. Features exercises, with answers to alternate questions, enabling use as a course text. Written at an elementary mathematical level so that readers with high school mathematics will find the content accessible. Graduate students studying genetic epidemiology, researchers and practitioners from genetics, epidemiology, biology, medical research and statistics will find this an invaluable introduction to statistics.
| Author | : Philip C. Nasca |
| Publisher | : Jones & Bartlett Learning |
| Total Pages | : 388 |
| Release | : 2001 |
| Genre | : Cancer |
| ISBN | : 9780834217768 |
Public Health
| Author | : Nan M. Laird |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 226 |
| Release | : 2010-12-13 |
| Genre | : Medical |
| ISBN | : 1441973389 |
This book covers the statistical models and methods that are used to understand human genetics, following the historical and recent developments of human genetics. Starting with Mendel’s first experiments to genome-wide association studies, the book describes how genetic information can be incorporated into statistical models to discover disease genes. All commonly used approaches in statistical genetics (e.g. aggregation analysis, segregation, linkage analysis, etc), are used, but the focus of the book is modern approaches to association analysis. Numerous examples illustrate key points throughout the text, both of Mendelian and complex genetic disorders. The intended audience is statisticians, biostatisticians, epidemiologists and quantitatively- oriented geneticists and health scientists wanting to learn about statistical methods for genetic analysis, whether to better analyze genetic data, or to pursue research in methodology. A background in intermediate level statistical methods is required. The authors include few mathematical derivations, and the exercises provide problems for students with a broad range of skill levels. No background in genetics is assumed.
| Author | : Alison Stewart |
| Publisher | : Cambridge University Press |
| Total Pages | : 291 |
| Release | : 2007-05-17 |
| Genre | : Medical |
| ISBN | : 1139463292 |
Genetics, Health Care and Public Policy is an introduction to the new discipline of public health genetics. It brings together the insights of genetic and molecular science as a means of protecting and improving the health of the population. Its scope is wide and requires an understanding of genetics, epidemiology, public health and the principles of ethics, law and the social sciences. This book sets out the basic principles of public health genetics for a wide audience from those providing health care to those involved in establishing policy. The emphasis throughout the text is on providing an accessible introduction to the field. The content moves from the basic concepts, including definitions and history, through chapters on genetics, genetic technology, epidemiology, genetics in medicine, genetics in health services, ethical, legal and social implications, to the implications for health policy. It provides one-stop, introductory coverage of this rapidly developing and multidisciplinary field.
| Author | : Robert H. Friis |
| Publisher | : Jones & Bartlett Learning |
| Total Pages | : 748 |
| Release | : 2009 |
| Genre | : Epidemiology |
| ISBN | : 9780763751616 |
Review: "Now in its Fourth Edition, this best-selling text offers comprehensive coverage of all the major topics in introductory epidemiology. With extensive treatment of the heart of epidemiology - from study designs to descriptive epidemiology to quantitative measures - this reader-friendly text is accessible and interesting to a wide range of beginning students in all health-related disciplines. A unique focus is given to real-world applications of epidemiology and the development of skills that students can apply in subsequent course work and in the field. The text is also accompanied by a complete package of instructor and student resources available through a companion Web site."--Jacket
| Author | : Roger Detels |
| Publisher | : Oxford University Press |
| Total Pages | : 1717 |
| Release | : 2017 |
| Genre | : Medical |
| ISBN | : 019881013X |
Sixth edition of the hugely successful, internationally recognised textbook on global public health and epidemiology, with 3 volumes comprehensively covering the scope, methods, and practice of the discipline
