This volume provides a critical response to the COVID-19 pandemic showcasing the full range of issues and perspectives that the discipline of geography can expose and bring to the table, not only to this specific event, but to others like it that might occur in future. Comprised of almost 60 short (2500 word) easy to read chapters, the collection provides numerous theoretical, empirical and methodological entry points to understanding the ways in which space, place and other geographical phenomenon are implicated in the crisis. Although falling under a health geography book series, the book explores the centrality and importance of a full range of biological, material, social, cultural, economic, urban, rural and other geographies. Hence the book bridges fields of study and sub-disciplines that are often regarded as separate worlds, demonstrating the potential for future collaboration and cross-disciplinary inquiry. Indeed book articulates a diverse but ultimately fulsome and multiscalar geographical approach to the major health challenge of our time, bringing different types of scholarship together with common purpose. The intended audience ranges from senior undergraduate students and graduate students to professional academics in geography and a host of related disciplines. These scholars might be interested in COVID-19 specifically or in the book’s broad disciplinary approach to infectious disease more generally. The book will also be helpful to policy-makers at various levels in formulating responses, and to general readers interested in learning about the COVID-19 crisis.