Handbook of Glycosyltransferases and Related Genes

Handbook of Glycosyltransferases and Related Genes
Author: Naoyuki Taniguchi
Publisher: Springer Science & Business Media
Total Pages: 668
Release: 2011-06-28
Genre: Science
ISBN: 4431678778

The so-called postgenomic research era has now been launched, and the field of gly cobiology and glycotechnology has become one of the most important areas in life science because glycosylation is the most common post-translational modification reaction of proteins in vivo. On the basis of Swiss-Prot data, over 50% proteins are known to undergo glycosylation, but in fact the actual functions of most of the sugar chains in the glycoconjugates remain unknown. The complex carbohydrate chains of glycoproteins, glycolipids, and proteoglycans represent the secondary gene products formed through the reactions of glycosyl transferases. The regulation of the biosynthesis of sugar chains is under the control of the expression of glycosyltransferases, their substrate specificity, and their local ization in specific tissue sites. There is a growing body of evidence to suggest that these enzymes play pivotal roles in a variety of important cellular differentiation and developmental events, as well as in disease processes. Over 300 glycosyltransferases appear to exist in mammalian tissues. If the genes that have been purified and cloned from various species such as humans, cattle, pigs, rats and mice are counted as one, approximately 110 glycogenes that encode glycosyltransferases and related genes have been cloned at present, and this number continues to grow each day. However, most of the functions of the glycosyltransferase genes and related genes are unknown. This fact has stimulated numerous new and interesting approaches in molecular biologi cal investigations.

Essentials of Glycobiology

Essentials of Glycobiology
Author: Ajit Varki
Publisher: CSHL Press
Total Pages: 694
Release: 1999
Genre: Medical
ISBN: 9780879696818

Sugar chains (glycans) are often attached to proteins and lipids and have multiple roles in the organization and function of all organisms. "Essentials of Glycobiology" describes their biogenesis and function and offers a useful gateway to the understanding of glycans.

The Molecular Immunology of Complex Carbohydrates-3

The Molecular Immunology of Complex Carbohydrates-3
Author: Albert M. Wu
Publisher: Springer Science & Business Media
Total Pages: 823
Release: 2011-05-27
Genre: Medical
ISBN: 1441978771

Based on the third symposium on “Molecular Immunology of Complex Carbohydrates,” this text covers the latest in glycotopes, structures and functions of complex carbohydrates, recognition factors of lectins, biomolecular interactions and other glycosciences. This volume highlights the informative events of the Symposium on Molecular Immunology of Complex Carbohydrates III, held at the Institute of Biological Chemistry, Academia Sinica, on July 15-20, 2007, in Taipei, Taiwan.

Neuroglycobiology

Neuroglycobiology
Author: Minoru Fukuda
Publisher: Oxford University Press, USA
Total Pages: 272
Release: 2005
Genre: Language Arts & Disciplines
ISBN: 9780198525387

Carbohydrates play a major role in brain function. In the past decade, tremendous progress has been made in understanding their structure and function within the nervous system. This book presents a state of the art account of this rapidly expanding field.

Gangliosides in Health and Disease

Gangliosides in Health and Disease
Author:
Publisher: Academic Press
Total Pages: 485
Release: 2018-04-25
Genre: Science
ISBN: 0128123427

Gangliosides in Health and Disease, Volume 156, presents the latest information on Gangliosides, a class of glycolipids that are found on all vertebrate cell surfaces, and are particularly abundant in the brain. Individual chapters in this new volume cover Gangliosides as Toxin Receptors, Gangliosides in Cancer Cell Signaling, Gangliosides in inflammation and neurodegeneration, Gangliosides as functional galectin receptors, Gangliosides in signal transduction, Gangliosides in brain tumor immunology, and Gangliosides in axon regeneration and stability, amongst other related topics. This book brings together world experts in ganglioside structure and function who have been assembled to contribute to this thorough update of the field. - Contains accessible content that is ideal for students and researchers alike - Written by leading authorities in the field

Human Chorionic Gonadotropin (hCG)

Human Chorionic Gonadotropin (hCG)
Author: Laurence A. Cole
Publisher: Elsevier
Total Pages: 405
Release: 2010-09-21
Genre: Science
ISBN: 012384908X

Human chorionic gonadotropin (hCG) is produced during pregnancy by the embryo. It promotes progesterone production by corpus luteal cells. It also functions in pregnancy to promote angiogenesis in uterine vasculature, it immuno-blands the invading placental tissue so it is not rejected by the maternal uterine tissues, promotes the growth of the uterus in line with the growth of the fetus, promotes the differentiation of growing cytotrophoblast cells, promotes the quiescence of contractions in the uterine myometrium during the course of pregnancy, and also has function in growth and development of fetal organs. The book describes the detailed biology, clinical chemistry, and clinical perspectives of hCG and associated molecules, and examines hCG, hyperglycosylated hCG and hCG free ß-subunit, 3 separate and independent molecules with totally sovereign physiological functions. - It provides comprehensive information on hCG from basic science to clinical medicine - Written by specialists in the field

Handbook of Vanilla Science and Technology

Handbook of Vanilla Science and Technology
Author: Daphna Havkin-Frenkel
Publisher: John Wiley & Sons
Total Pages: 524
Release: 2018-09-24
Genre: Technology & Engineering
ISBN: 1119377277

An updated guide to the production, science, and uses of vanilla Vanilla is a flavor and fragrance in foods, cosmetics, pharmaceuticals, and a wealth of other products. Now in its second edition, the Handbook of Vanilla Science and Technology provides a comprehensive and updated review of the science and technology used in these items’ production and supply. Featuring contributions from an international range of experts, this revised edition covers a multitude of topics, including agricultural production, global markets, analytical methods, sensory analysis, food and fragrance applications, organic farming and fair trade, botanical diseases, and novel uses. The Handbook of Vanilla Science and Technology, Second Edition is a vital resource for producers, distributors, and scientists involved in vanilla’s growth and utilization, and offers readers: A guide to the cultivation, extraction, analysis, DNA sequencing, and marketing of vanilla Information on the production of vanilla in a range of countries such as Mexico, Australia, Costa Rica, and India Guidelines on the quality control of vanilla beans and extracts Information on fair trade and the future of vanilla

The Glycome

The Glycome
Author: Adeel Malik
Publisher: CRC Press
Total Pages: 305
Release: 2021-07-07
Genre: Science
ISBN: 1000344320

This volume provides a comprehensive understanding of the enigmatic identity of the glycome, a complex but important area of research that has been largely ignored due to its complexity. The authors thoroughly deal with almost all aspects of the glycome, i.e., elucidation of the glycan identity enigma and its role in regulation of the cellular process, and in disease etiology. The book bridges the knowledge gap in understanding the glycome, from being a cell signature to its applications in disease etiology. In addition, it details many of the major insights regarding the possible role of the glycome in various diseases as a therapeutic marker. The book systematically covers the major aspects of the glycome, including the significance of substituting the diverse monosaccharide units to glycoproteins, the role of glycans in disease pathologies, and the challenges and advances in glycobiology. The authors stress the significance and huge encoding power of carbohydrates as well as provide helpful insights in framing the bigger picture. The Glycome: Understanding the Diversity and Complexity of Glycobiology details state-of-the-art developments and emerging challenges of glycome biology, which are going to be key areas of future research, not only in the glycobiology field but also in pharmaceutics.