This book constitutes the extended abstracts of the posters presented during the 22nd International Conference on Human-Computer Interaction, HCII 2020, which was held in July 2020. The conference was planned to take place in Copenhagen, Denmark, but had to change to a virtual conference mode due to the COVID-19 pandemic. From a total of 6326 submissions, a total of 1439 papers and 238 posters have been accepted for publication in the HCII 2020 proceedings before the conference took place. In addition, a total of 333 papers and 144 posters are included in the volumes of the proceedings published after the conference as “Late Breaking Work” (papers and posters). These contributions address the latest research and development efforts in the field and highlight the human aspects of design and use of computing systems. The 82 papers presented in this volume are organized in topical sections as follows: design for all and sssisitive technologies; virtual, augmented and mixed reality; learning; HCI, culture and art; health and wellbeing applications; HCI in mobility, automotive and aviation.