In an era of rapid technological advancements, libraries have evolved to cater to the changing needs and aspirations of users and society at large. IT has emerged as a critical factor in this transformation, empowering libraries to offer faster, more efficient, and highly convenient services to their users. The Handbook of Research on Innovative Approaches to Information Technology in Library and Information Science is a comprehensive guide that delves into the dynamic relationship between libraries, information centers, and information technology (IT). Within the pages of this edited research handbook, a team of esteemed scholars and experts in the field explore the multifaceted applications of IT in libraries and information centers. They delve into the effective management of collections, resources, and operations, shedding light on how technology can optimize these vital aspects of library services. From information centers that curate and provide access, to diverse information resources, to the revolutionary impact of IT in digitizing libraries, this handbook covers a wide range of topics relevant to contemporary library and information science. This book address crucial themes such as artificial intelligence, data science, computer science, information management, metadata, cybersecurity, machine learning, chatbots, mobile services, and robotics. It explores the integration of these cutting-edge technologies within the realm of libraries, examining how they enhance efficiency, user experience, and digital equity. By addressing the challenges and opportunities presented by IT, this handbook equips librarians, information professionals, researchers, professors, advanced students, and practitioners with the knowledge and insights needed to navigate the rapidly evolving landscape of library and information science.