Maladies of Empire

Maladies of Empire
Author: Jim Downs
Publisher: Harvard University Press
Total Pages: 273
Release: 2021-01-12
Genre: Science
ISBN: 0674971728

A sweeping global history that looks beyond European urban centers to show how slavery, colonialism, and war propelled the development of modern medicine. Most stories of medical progress come with ready-made heroes. John Snow traced the origins of LondonÕs 1854 cholera outbreak to a water pump, leading to the birth of epidemiology. Florence NightingaleÕs contributions to the care of soldiers in the Crimean War revolutionized medical hygiene, transforming hospitals from crucibles of infection to sanctuaries of recuperation. Yet histories of individual innovators ignore many key sources of medical knowledge, especially when it comes to the science of infectious disease. Reexamining the foundations of modern medicine, Jim Downs shows that the study of infectious disease depended crucially on the unrecognized contributions of nonconsenting subjectsÑconscripted soldiers, enslaved people, and subjects of empire. Plantations, slave ships, and battlefields were the laboratories in which physicians came to understand the spread of disease. Military doctors learned about the importance of air quality by monitoring Africans confined to the bottom of slave ships. Statisticians charted cholera outbreaks by surveilling Muslims in British-dominated territories returning from their annual pilgrimage. The field hospitals of the Crimean War and the US Civil War were carefully observed experiments in disease transmission. The scientific knowledge derived from discarding and exploiting human life is now the basis of our ability to protect humanity from epidemics. Boldly argued and eye-opening, Maladies of Empire gives a full account of the true price of medical progress.

Maladies of Empire

Maladies of Empire
Author: Jim Downs
Publisher: Harvard University Press
Total Pages: 273
Release: 2021-09-07
Genre: Science
ISBN: 0674249887

A sweeping global history that looks beyond European urban centers to show how slavery, colonialism, and war propelled the development of modern medicine. Most stories of medical progress come with ready-made heroes. John Snow traced the origins of London’s 1854 cholera outbreak to a water pump, leading to the birth of epidemiology. Florence Nightingale’s contributions to the care of soldiers in the Crimean War revolutionized medical hygiene, transforming hospitals from crucibles of infection to sanctuaries of recuperation. Yet histories of individual innovators ignore many key sources of medical knowledge, especially when it comes to the science of infectious disease. Reexamining the foundations of modern medicine, Jim Downs shows that the study of infectious disease depended crucially on the unrecognized contributions of nonconsenting subjects—conscripted soldiers, enslaved people, and subjects of empire. Plantations, slave ships, and battlefields were the laboratories in which physicians came to understand the spread of disease. Military doctors learned about the importance of air quality by monitoring Africans confined to the bottom of slave ships. Statisticians charted cholera outbreaks by surveilling Muslims in British-dominated territories returning from their annual pilgrimage. The field hospitals of the Crimean War and the US Civil War were carefully observed experiments in disease transmission. The scientific knowledge derived from discarding and exploiting human life is now the basis of our ability to protect humanity from epidemics. Boldly argued and eye-opening, Maladies of Empire gives a full account of the true price of medical progress.

The Emperor of All Maladies

The Emperor of All Maladies
Author: Siddhartha Mukherjee
Publisher: Simon and Schuster
Total Pages: 624
Release: 2011-08-09
Genre: Health & Fitness
ISBN: 1439170916

Winner of the Pulitzer Prize and a documentary from Ken Burns on PBS, this New York Times bestseller is “an extraordinary achievement” (The New Yorker)—a magnificent, profoundly humane “biography” of cancer—from its first documented appearances thousands of years ago through the epic battles in the twentieth century to cure, control, and conquer it to a radical new understanding of its essence. Physician, researcher, and award-winning science writer, Siddhartha Mukherjee examines cancer with a cellular biologist’s precision, a historian’s perspective, and a biographer’s passion. The result is an astonishingly lucid and eloquent chronicle of a disease humans have lived with—and perished from—for more than five thousand years. The story of cancer is a story of human ingenuity, resilience, and perseverance, but also of hubris, paternalism, and misperception. Mukherjee recounts centuries of discoveries, setbacks, victories, and deaths, told through the eyes of his predecessors and peers, training their wits against an infinitely resourceful adversary that, just three decades ago, was thought to be easily vanquished in an all-out “war against cancer.” The book reads like a literary thriller with cancer as the protagonist. Riveting, urgent, and surprising, The Emperor of All Maladies provides a fascinating glimpse into the future of cancer treatments. It is an illuminating book that provides hope and clarity to those seeking to demystify cancer.

Network Medicine

Network Medicine
Author: Joseph Loscalzo
Publisher: Harvard University Press
Total Pages: 449
Release: 2017-02-01
Genre: Medical
ISBN: 0674436539

Big data, genomics, and quantitative approaches to network-based analysis are combining to advance the frontiers of medicine as never before. Network Medicine introduces this rapidly evolving field of medical research, which promises to revolutionize the diagnosis and treatment of human diseases. With contributions from leading experts that highlight the necessity of a team-based approach in network medicine, this definitive volume provides readers with a state-of-the-art synthesis of the progress being made and the challenges that remain. Medical researchers have long sought to identify single molecular defects that cause diseases, with the goal of developing silver-bullet therapies to treat them. But this paradigm overlooks the inherent complexity of human diseases and has often led to treatments that are inadequate or fraught with adverse side effects. Rather than trying to force disease pathogenesis into a reductionist model, network medicine embraces the complexity of multiple influences on disease and relies on many different types of networks: from the cellular-molecular level of protein-protein interactions to correlational studies of gene expression in biological samples. The authors offer a systematic approach to understanding complex diseases while explaining network medicine’s unique features, including the application of modern genomics technologies, biostatistics and bioinformatics, and dynamic systems analysis of complex molecular networks in an integrative context. By developing techniques and technologies that comprehensively assess genetic variation, cellular metabolism, and protein function, network medicine is opening up new vistas for uncovering causes and identifying cures of disease.

Cardiovascular Diseases in the United States

Cardiovascular Diseases in the United States
Author: Iwao Milton Moriyama
Publisher: Harvard University Press
Total Pages: 530
Release: 1971
Genre: Cardiovascular system
ISBN: 9780674096400

Cardiovascular diseases kill and disable more than a million Americans each year. The major types of this complex of diseases are coronary heart disease, hypertensive disease, cerebrovascular diseases, rheumatic heart disease, and congenital malformations of the circulatory system. Authors Moriyama, Krueger, and Stamler relate each of these types to etiology, age of patient at onset, clinical course, and socioeconomic impact on the population. For each type of cardiovascular disease they analyze the quantitative data on the incidence, prevalence, and levels and time trends of mortality and on the demographic characteristics of person affected. They also examine international differences in levels and trends in mortality and point out areas for further research. More than thirty-five figures as well as extensive tables document their text.

Sick from Freedom

Sick from Freedom
Author: Jim Downs
Publisher: OUP USA
Total Pages: 279
Release: 2012-05-14
Genre: History
ISBN: 0199758727

Sick from Freedom provides the first study of the health conditions of emancipated slaves and reveals the epidemics, illnesses, and poverty that former slaves suffered from when slavery ended and freedom began.

Beyond Freedom

Beyond Freedom
Author: David W. Blight
Publisher: University of Georgia Press
Total Pages: 210
Release: 2017-11-01
Genre: Social Science
ISBN: 0820351474

This collection of eleven original essays interrogates the concept of freedom and recenters our understanding of the process of emancipation. Who defined freedom, and what did freedom mean to nineteenth-century African Americans, both during and after slavery? Did freedom just mean the absence of constraint and a widening of personal choice, or did it extend to the ballot box, to education, to equality of opportunity? In examining such questions, rather than defining every aspect of postemancipation life as a new form of freedom, these essays develop the work of scholars who are looking at how belonging to an empowered government or community defines the outcome of emancipation. Some essays in this collection disrupt the traditional story and time-frame of emancipation. Others offer trenchant renderings of emancipation, with new interpretations of the language and politics of democracy. Still others sidestep academic conventions to speak personally about the politics of emancipation historiography, reconsidering how historians have used source material for understanding subjects such as violence and the suffering of refugee women and children. Together the essays show that the question of freedom—its contested meanings, its social relations, and its beneficiaries—remains central to understanding the complex historical process known as emancipation. Contributors: Justin Behrend, Gregory P. Downs, Jim Downs, Carole Emberton, Eric Foner, Thavolia Glymph, Chandra Manning, Kate Masur, Richard Newman, James Oakes, Susan O’Donovan, Hannah Rosen, Brenda E. Stevenson.

The Ends of Human Life

The Ends of Human Life
Author: Ezekiel J. Emanuel
Publisher: Harvard University Press
Total Pages: 326
Release: 1991
Genre: Bioethics
ISBN: 9780674253261

Emanual (oncology and medical ethics, Harvard) rejects the argument that recent issues of medical ethics are the result of new technologies, and contends that they are an inevitable consequence of liberal political values. He proposes a communitarian solution. Annotation copyrighted by Book News, Inc., Portland, OR

Stand by Me

Stand by Me
Author: Jim Downs
Publisher: Basic Books
Total Pages: 273
Release: 2016-03-01
Genre: History
ISBN: 046509855X

From a prominent young historian, the untold story of the rich variety of gay life in America in the 1970s Despite the tremendous gains of the LGBT movement in recent years, the history of gay life in this country remains poorly understood. According to conventional wisdom, gay liberation started with the Stonewall Riots in Greenwich Village in 1969. The 1970s represented a moment of triumph -- both political and sexual -- before the AIDS crisis in the subsequent decade, which, in the view of many, exposed the problems inherent in the so-called "gay lifestyle". In Stand by Me, the acclaimed historian Jim Downs rewrites the history of gay life in the 1970s, arguing that the decade was about much more than sex and marching in the streets. Drawing on a vast trove of untapped records at LGBT community centers in Los Angeles, New York, and Philadelphia, Downs tells moving, revelatory stories of gay people who stood together -- as friends, fellow believers, and colleagues -- to create a sense of community among people who felt alienated from mainstream American life. As Downs shows, gay people found one another in the Metropolitan Community Church, a nationwide gay religious group; in the pages of the Body Politic, a newspaper that encouraged its readers to think of their sexuality as a political identity; at the Oscar Wilde Memorial Bookstore, the hub of gay literary life in New York City; and at theaters putting on "Gay American History," a play that brought to the surface the enduring problem of gay oppression. These and many other achievements would be largely forgotten after the arrival in the early 1980s of HIV/AIDS, which allowed critics to claim that sex was the defining feature of gay liberation. This reductive narrative set back the cause of gay rights and has shaped the identities of gay people for decades. An essential act of historical recovery, Stand by Me shines a bright light on a triumphant moment, and will transform how we think about gay life in America from the 1970s into the present day.