Melanins and Melanogenesis

Melanins and Melanogenesis
Author: Giuseppe Prota
Publisher: Academic Press
Total Pages: 305
Release: 2012-12-02
Genre: Science
ISBN: 0323139396

This volume covers all aspects of melanin pigmentation, providing a concise, comprehensive picture of new knowledge gained at the frontiers of research. It draws heavily on the author's 30-year activity in the field and his continuing work with specialists of widely diverse disciplines. The core of the volume deals with the structure, physicochemical properties, and biosynthesis of the major classes of melanin pigments, including neuromelanins. Further discussions include the biology of the various types of pigment-producing cells, the structure and mode of action of tyrosinase, and the chemistry of urinary melanogens and their biomedical applications as metabolic markers of melanocyte activity, especially for the follow-up of malignant melanoma. Finally, the volume considers progress in the photobiology and photochemistry of melanins, with special emphasis on the controversial role of these pigments in skin photoprotection. Melanins and Melanogenesis is ideally suited as a basic guide for newcomers, and a handy source of specific information for practitioners in academic, medical, and industrial settings.

Melanins and Melanosomes

Melanins and Melanosomes
Author: Jan Borovansky
Publisher: John Wiley & Sons
Total Pages: 395
Release: 2011-10-05
Genre: Science
ISBN: 3527644555

The surface pigmentation of vertebrates is controlled by specialized cells able to synthesize a variety of pigments collectively known as melanins. Recent research has shown that melanins are produced not only in the skin but also in many other sites such as the eye, inner ear, muscles, etc., - where they are engaged in some unanticipated roles. The details of the synthetic pathway, the complexities of its regulation and biological significance that have been unravelled in recent research comprise a fascinating story and are of key importance in understanding the nature of diseases, including malignant melanoma one of the most rapidly spreading cancers.

The Pigmentary System

The Pigmentary System
Author: James J. Nordlund
Publisher: John Wiley & Sons
Total Pages: 1333
Release: 2008-04-15
Genre: Medical
ISBN: 140515733X

The most comprehensive and integrated book on pigmentation The Pigmentary System, Second Edition, gathers into one convenient, all-inclusive volume a wealth of information about the science of pigmentation and all the common and rare clinical disorders that affect skin color. The two parts, physiology (science) and pathophysiology (clinical disorders), are complementary and annotated so that those reading one part can easily refer to relevant sections in the other. For the clinician interested in common or rare pigment disorders or the principles of teaching about such disorders, this book provides an immediate and complete resource on the biologic bases for these disorders. For the scientist studying the biology of melanocyte function, the book provides a list of disorders that are related to basic biological functions of melanocytes. New features of this Second Edition include: Completely new section on the basic science of pigmentation – explaining the integration of melanocyte functions with other epidermal cells and with various organ systems like the immune system New chapters on pigmentary disorders related to intestinal diseases, the malignant melanocyte, benign proliferations of melanocytes (nevi) and phototherapy with narrow band UV All clinical chapters include the latest genetic findings and advances in therapy More than 400 color images of virtually all clinical disorders The book is ideal for all dermatologists and especially those interested in disorders of pigmentation. It is of particular use for pediatric dermatologists and medical geneticists caring for patients with congenital and genetic pigmentary disorders. This authoritative volume will fill the gap for dermatology training programs that do not have local experts on pigmentation. Basic and cosmetic scientists studying pigmentation and melanocytes will find the science and clinical correlations very useful in showing human significance and relevance to the results of their studies.

Melanin

Melanin
Author: Miroslav Blumenberg
Publisher: BoD – Books on Demand
Total Pages: 116
Release: 2017-03-01
Genre: Science
ISBN: 9535129791

The word melanin refers to dark natural pigments produced by the oxidative degradation of tyrosine, catalyzed by tyrosinase, and polymerized into insoluble granular substance. The main function of melanin is to protect from harmful agents, primarily UV radiation, but also from oxidation, heavy metals, etc. In this volume, chapters deal with production of melanin in human oral mucosa (Liviu et al.), the regulation of melanin action (Cecile et al.), production and potential technological application of fungal melanins (Pombiero-Sponchiado et al.) and an innovative method for measuring melanin in various samples (Zdybel et al.). In conclusion, this volume presents various biological and industrial aspects of melanin production, uses and analysis.

In the Light of Evolution

In the Light of Evolution
Author: National Academy of Sciences
Publisher:
Total Pages: 388
Release: 2007
Genre: Science
ISBN:

The Arthur M. Sackler Colloquia of the National Academy of Sciences address scientific topics of broad and current interest, cutting across the boundaries of traditional disciplines. Each year, four or five such colloquia are scheduled, typically two days in length and international in scope. Colloquia are organized by a member of the Academy, often with the assistance of an organizing committee, and feature presentations by leading scientists in the field and discussions with a hundred or more researchers with an interest in the topic. Colloquia presentations are recorded and posted on the National Academy of Sciences Sackler colloquia website and published on CD-ROM. These Colloquia are made possible by a generous gift from Mrs. Jill Sackler, in memory of her husband, Arthur M. Sackler.

Insect Immunity

Insect Immunity
Author: Petros Ligoxygakis
Publisher: Academic Press
Total Pages: 0
Release: 2017-05-25
Genre: Science
ISBN: 9780128117750

Insect Immunity, Volume 52 provides readers with the latest interdisciplinary reviews on the topic. It is an essential reference source for invertebrate physiologists, neurobiologists, entomologists, zoologists and insect chemists, providing invaluable chapters on Insect Antimicrobial Defenses: A Brief History, Recent Findings, Biases, and a Way Forward in Evolutionary Studies, Phagocytosis in Insect Immunity, The Melanization Response in Insect Immunity, Microbiota, Gut Physiology, and Insect Immunity, Intestinal Stem Cells: A Decade of Intensive Research in Drosophila and the Road Ahead, and Insect Symbiosis and Immunity: The Bean Bug-Burkholderia Interaction as a Case Study, along with other related topics.

Cutaneous Melanoma

Cutaneous Melanoma
Author: Charles M. Balch
Publisher: Springer
Total Pages: 0
Release: 2020-01-29
Genre: Medical
ISBN: 9783030050689

Written by the leading melanoma experts from the United States, Australia, and Europe, this new edition incorporates the clinical outcomes of more than 70,000 patients treated at major melanoma centers throughout the world and is the definitive and most authoritative textbook on melanoma used worldwide. Providing the most up-to-date and comprehensive information needed for the clinical management and scientific study of melanoma, Cutaneous Melanoma, 6th edition covers everything from precursors of melanoma to advanced stages of metastatic disease.

Pigments, Pigment Cells and Pigment Patterns

Pigments, Pigment Cells and Pigment Patterns
Author: Hisashi Hashimoto
Publisher: Springer Nature
Total Pages: 475
Release: 2021-07-05
Genre: Science
ISBN: 9811614903

This book comprehensively summarizes the biological mechanisms of coloration and pattern formation of animals at molecular and cellular level, offering up-to-date knowledge derived from remarkable progress in the last 10 years. The brilliant coloration, conspicuous patterns and spectacular color changes displayed by some vertebrates and invertebrates are generally their strategies of the utmost importance for survival. Consists of mainly three parts, starts with introductory chapter, such as Pigments and Pigment Organelles, Developmental Genetics of Pigment Cell Formation, Adult Pigment Patterns, and Color Changes, this book introduces new pigment compounds in addition to classically known pigments and organelles, explains how the generation of multiple types of pigment cell is genetically controlled, describes the mechanisms underlying the zebrafish stripe formation as well as other animals and also summarizes the mechanism of physiological and morphological color changes of teleost, amphibian and cephalopod. Written by experts in the field, this book will be essential reading for graduate students and researchers in biological fields who are interested in pigmentation mechanisms of animals.

Catecholamine Research

Catecholamine Research
Author: Toshiharu Nagatsu
Publisher: Springer Science & Business Media
Total Pages: 586
Release: 2002-10-31
Genre: Medical
ISBN: 9780306474033

The field of catecholamine research has not undergone comprehensive review for four years. In the interim, a tremendous amount of new information, obtained using molecular, genetic, neurochemical, and nuclear scanning techniques, has substantiated the important roles of catecholamine systems in development, cardiovascular function, psychiatric disorders, neurodegenerative diseases, and metabolism. This volume, based on the Ninth International Catecholamine Symposium, will have a substantial and lasting impact on medical science.