Neuroglycobiology

Neuroglycobiology
Author: Minoru Fukuda
Publisher: Oxford University Press, USA
Total Pages: 272
Release: 2005
Genre: Language Arts & Disciplines
ISBN: 9780198525387

Carbohydrates play a major role in brain function. In the past decade, tremendous progress has been made in understanding their structure and function within the nervous system. This book presents a state of the art account of this rapidly expanding field.

Structure and Function of the Neural Cell Adhesion Molecule NCAM

Structure and Function of the Neural Cell Adhesion Molecule NCAM
Author: Vladimir Berezin
Publisher: Springer Science & Business Media
Total Pages: 429
Release: 2009-12-17
Genre: Medical
ISBN: 1441911707

This book describes recent developments concerning structural, functional and possible therapeutic aspects of one particular CAM, the neural cell adhesion molecule (NCAM).

Functional Glycomics

Functional Glycomics
Author:
Publisher: Academic Press
Total Pages: 513
Release: 2010-10-25
Genre: Science
ISBN: 0123809983

In this 3 volume collection focusing on glycomics, readers will appreciate how such discoveries were made and how such methods can be applied for readers' own research efforts - Each chapter has been designed so that enough scientific background will be given in each chapter for further development of methods by readers themselves - Useful for all levels of scientists starting from the last years of colleges, graduate students, postdoctoral fellows to professors and to all levels of scientists in research institutes including industry

Fungal Lipid Biochemistry

Fungal Lipid Biochemistry
Author: Yuanda Song
Publisher: Bentham Science Publishers
Total Pages: 360
Release: 2023-07-26
Genre: Science
ISBN: 9815123025

Fungal Lipid Biochemistry explores the intricate biochemistry of fungal and microbial lipids. The book focuses on recent advances in our knowledge about the distribution, classification, and biochemistry of fungal lipids. The book is divided into four sections, starting with an introduction to fungal lipids which includes definition, classification, nomenclature, and some historical aspects of fungal lipid research. This is followed by an overview of fungal lipids, and environmental and nutritional cultural conditions affecting lipid production. The second section contains four chapters that explain the metabolism of fatty acids, their biosynthetic pathways together with their storage mainly in the form of triacylglycerols. The latter includes a key description of the recently discovered lipid droplet acting as a highly specific cellular compartment for the storage of neutral lipids. The third section contains five chapters concerned with the relatively recent interpretation of other major lipid classes which include glycerophospholipids, sphingolipids, aliphatic hydrocarbons, sterols, carotenoids, and polyprenols and their occurrence and biosynthesis. The final section covers lipid metabolism during fungal development and sporulation. Key features - Extensive coverage of fungal lipid biochemistry, with a focus on recent knowledge - Includes chapters for specific lipid classes with notes on their metabolism - Gives knowledge about the role of lipids in fungal growth and development - Provides references for further reading This book is a comprehensive reference for academics, scientific researchers, and industrial scientists (in biotechnology, food science and nutritional health) who require information about fungal lipid composition and biochemistry.

Neurobiology of Glycoconjugates

Neurobiology of Glycoconjugates
Author: R.K. Margolis
Publisher: Springer Science & Business Media
Total Pages: 463
Release: 2013-04-18
Genre: Science
ISBN: 147575955X

This revised and renamed volume reflects a number of important changes in content and emphasis since this field was first surveyed in Complex carbohydrates of nervous tissue in 1979. A third of the chapters did not appear in the predecessor volume, and more than half have new authors. In this expand

Neurobiology of Alzheimer's Disease

Neurobiology of Alzheimer's Disease
Author: David Dawbarn
Publisher:
Total Pages: 495
Release: 2007
Genre: Medical
ISBN: 0198566611

Alzheimer's disease is the most common form of dementia in the elderly; 450,000 people in the UK and 4.5 million people in the USA suffer with this disease. This 3rd edition of Neurobiology of Alzheimer's Disease gives a comprehensive and readable introduction to the disease, from molecular pathology to clinical practice. The book is intended for readers new to the field, and it also covers an extensive range of themes for those with in-depth knowledge of Alzheimer's disease. It will therefore act either as an introduction to the whole field of neurodegeneration or it will help experienced researchers to access the latest research in specialist topics. Each chapter is written by eminent scientists leading their fields in neuropathology, clinical practice and molecular neurobiology; appendices detail disease-associate proteins, their sequences, familial mutations and known structures. It will be essential reading for students interested in neurodegeneration and for researchers and clinicians, giving a coherent and cohesive approach to the whole area of research, and allowing access at different levels. For those in the pharmaceutical industry it describes the underlying molecular mechanisms involved in the pathogenesis of Alzheimer's disease and explains how current and potential therapeutics may work.

Science

Science
Author: John Michels (Journalist)
Publisher:
Total Pages: 618
Release: 2004
Genre: Science
ISBN:

A weekly record of scientific progress.

Translational Glycobiology in Human Health and Disease

Translational Glycobiology in Human Health and Disease
Author: Michelle Kilcoyne
Publisher: Academic Press
Total Pages: 464
Release: 2023-11-29
Genre: Science
ISBN: 0128220023

Along with nucleic acids, proteins, and lipids, carbohydrates stand as one of four main components of cellular architecture. However, glycobiology (or carbohydrate bioscience) is little understood by non-experts, partly because carbohydrates are a complex, diverse class of molecules structurally and functionally. In recent years, advances in computational analytics (glycomics) have allowed us to better interpret and realize the importance of glycobiology in human health and disease, and glycans and their associated processes have been shown to play a significant role across a variety of disease types. As the biomedical sciences continue to adopt multi-omic and precision medicine approaches, a greater understanding of glycobiology is essential for maintaining healthy physiology and advancing disease treatment.Translational Glycobiology in Human Health and Disease offers a deep examination of glycobiology for experts and non-experts alike in areas ranging from the role of glycobiology in chronic and infectious diseases to advances in technologies for higher throughput analysis and diagnosis. While keeping human health in the forefront, this book integrates a thorough discussion of glycobiology fundamentals with its growing areas of application and societal impact. With emphasis throughout on the interdisciplinary nature of glycosciences, this book also features perspectives from the health, computational (glycoanalytics), materials, biopharmaceutical, and diagnostic sciences.Disease and speciality areas addressed include gycoimmunology, neuroglycobiology, commensal glycobiology, gut health, regenerative medicine and glycobiology, glycobiology and cancer, congenital disorders of glycosylation, infectious disease glycobiology, and parasite glycobiology. Computational approaches discussed, supporting the advance of new research, include advanced glycoanalytics, glycomics microarrays, glycoengineering, and glycol systems biology. Additionally, authors consider impact areas for society and public health, such as glycobiology and entrepreneurship, policy and regulatory requirements for glycosylation, future research, and translation to new diagnostics and drug discovery. - Provides a deep, foundational overview of glycoscience and its translational potential, highlighting glycobiology's growing role in human health and disease study - Examines a broad range of relevant disease areas and applications of glycobiology in policy and public health - Features chapter contributions from leading, international experts in the field, fully integrating perspectives from the health, computational, materials, biopharmaceutical, and diagnostic sciences

Autophagy Dysfunction in Alzheimer's Disease and Dementia

Autophagy Dysfunction in Alzheimer's Disease and Dementia
Author: Tadanori Hamano
Publisher: Academic Press
Total Pages: 360
Release: 2022-08-20
Genre: Medical
ISBN: 0323899145

Autophagy Dysfunction in Alzheimer’s Disease and Dementia provides an overview for researchers and clinicians on the mechanisms involved in protein degradation in Alzheimer’s. The book discusses the implication of autophagy dysfunction in these diseases and how it causes degenerated proteins, including aggregated tau and aggregated amyloid protein. Other sections explores the possibilities of potential drug development through autophagy modulation, making this a great resource on the study of how autophagy dysfunction has been linked to the accumulation of misfolded proteins that cause death of neurons in Alzheimer’s and other neurodegenerative diseases. Discusses the implication of autophagy dysfunction in neurodegenerative diseases Highlights the mechanisms involved in protein degradation Explores the possibilities of drug development through autophagy modulation