In 1951 Evelyn Russell, middle-aged wife of a Mississippi sharecropper, uses a spool of thread and finds written on the empty spool the name and address of Paula Tillman, a young cotton mill worker in Maine. Evie writes to Paula, and thus begins a two-decade pen-pal friendship between the two women. Structured around the letters the women exchange over the years, A Spool of Thread recounts the experiences of two families that never meet but are linked by their shared joys and challenges, heartaches and triumphs. The thread of the novel is the fragile and precious thread of life, woven into a story celebrating our common humanity.