Radiotherapy of Liver Cancer

Radiotherapy of Liver Cancer
Author: Jinsil Seong
Publisher: Springer
Total Pages: 337
Release: 2022-07-02
Genre: Medical
ISBN: 9789811618178

This book provides up-to-date information on all aspects of radiotherapy for liver cancer, from the basic science to clinical practice. While demand for radiotherapy of liver cancer has been increasing, the guidance available to clinicians has remained limited. Radiotherapy of Liver Cancer aims to address this deficit on the basis of the best available evidence. The first two sections explain the relevant basic science and present detailed information on the available technologies and techniques, including the most recent advances. The radiotherapy strategies appropriate in different patient groups are then fully described, covering the use of ablative, adjuvant, neoadjuvant, and definitive radiotherapy, radiotherapy as a bridge to liver transplantation, and palliative radiotherapy. The final section addresses a range of specific issues of concern to the clinician. Radiotherapy of Liver Cancer will be an ideal reference for clinical radiation oncologists, radiation oncology residents, oncologists, and hepatologists.

Carbon-Ion Radiotherapy

Carbon-Ion Radiotherapy
Author: Hirohiko Tsujii
Publisher: Springer Science & Business Media
Total Pages: 284
Release: 2013-12-25
Genre: Medical
ISBN: 4431544577

This book serves as a practical guide for the use of carbon ions in cancer radiotherapy. On the basis of clinical experience with more than 7,000 patients with various types of tumors treated over a period of nearly 20 years at the National Institute of Radiological Sciences, step-by-step procedures and technological development of this modality are highlighted. The book is divided into two sections, the first covering the underlying principles of physics and biology, and the second section is a systematic review by tumor site, concentrating on the role of therapeutic techniques and the pitfalls in treatment planning. Readers will learn of the superior outcomes obtained with carbon-ion therapy for various types of tumors in terms of local control and toxicities. It is essential to understand that the carbon-ion beam is like a two-edged sword: unless it is used properly, it can increase the risk of severe injury to critical organs. In early series of dose-escalation studies, some patients experienced serious adverse effects such as skin ulcers, pneumonitis, intestinal ulcers, and bone necrosis, for which salvage surgery or hospitalization was required. To preclude such detrimental results, the adequacy of therapeutic techniques and dose fractionations was carefully examined in each case. In this way, significant improvements in treatment results have been achieved and major toxicities are no longer observed. With that knowledge, experts in relevant fields expand upon techniques for treatment delivery at each anatomical site, covering indications and optimal treatment planning. With its practical focus, this book will benefit radiation oncologists, medical physicists, medical dosimetrists, radiation therapists, and senior nurses whose work involves radiation therapy, as well as medical oncologists and others who are interested in radiation therapy.

Liver Malignancies

Liver Malignancies
Author: Carlo Bartolozzi
Publisher: Springer Science & Business Media
Total Pages: 570
Release: 1999
Genre: Diagnostic imaging
ISBN: 9783540647560

This book provides a comprehensive and up-to-date overview of the role of diagnostic and interventional radiology in respect of liver malignancies. Following background chapters on anatomy, epidemiology, and clinicopathologic features, each of the diagnostic imaging techniques is carefully appraised, focusing on new developments in equipment and contrast agents. The interventional therapeutic approaches to primary and secondary hepatic malignancies are then discussed in depth. The volume also covers special topics such as liver tumors in children and hepatic transplantation. This book, written by leading experts from throughout the world, will prove an indispensable source of information for clinicians and researchers involved in the diagnostic and therapeutic management of patients with liver malignancies.

Stereotactic Body Radiation Therapy

Stereotactic Body Radiation Therapy
Author: Simon S. Lo
Publisher: Springer Science & Business Media
Total Pages: 433
Release: 2012-08-28
Genre: Medical
ISBN: 364225604X

Stereotactic body radiation therapy (SBRT) has emerged as an important innovative treatment for various primary and metastatic cancers. This book provides a comprehensive and up-to-date account of the physical/technological, biological, and clinical aspects of SBRT. It will serve as a detailed resource for this rapidly developing treatment modality. The organ sites covered include lung, liver, spine, pancreas, prostate, adrenal, head and neck, and female reproductive tract. Retrospective studies and prospective clinical trials on SBRT for various organ sites from around the world are examined, and toxicities and normal tissue constraints are discussed. This book features unique insights from world-renowned experts in SBRT from North America, Asia, and Europe. It will be necessary reading for radiation oncologists, radiation oncology residents and fellows, medical physicists, medical physics residents, medical oncologists, surgical oncologists, and cancer scientists.

Liver Cancer in the Middle East

Liver Cancer in the Middle East
Author: Brian I. Carr
Publisher: Springer Nature
Total Pages: 408
Release: 2021-09-22
Genre: Medical
ISBN: 3030787370

This book aims to illuminate the causes, incidence, and treatments of Hepatocellular Carcinoma(HCC) or liver cancer in the politically important and societally diverse region of the Middle East. Taking a flexible and inclusive view, it examines the influences of geography, crops and diet, ethnicity, and local behavior on both diagnosis and outcomes of this disease. Understanding the different causes of liver cancer enables effective strategies for both prevention and early diagnosis while knowledge of the different treatment modalities, their uses and limitations, availability and costs, works to inform rational treatment provision and selection. Divided into four sections, this book considers the causes and clinical syndromes associated with HCC, provides a detailed overview of clinical HCC and treatment modalities, describes country-specific clinical HCC experience and practice, and considers future needs and the potential for HCC collaborations across the region. Liver Cancer in the Middle East is a useful resource for clinicians seeking insight into the second highest cause of death from cancer worldwide, governments planning social and medical services for their peoples, as well as for international aid agencies prioritizing donations.

Radiation Therapy for Liver Tumors

Radiation Therapy for Liver Tumors
Author: Jeffrey Meyer
Publisher: Springer
Total Pages: 285
Release: 2017-07-02
Genre: Medical
ISBN: 3319545310

The management of liver tumors is a nexus of interactions among multiple medical specialties, including radiation oncology. A multitude of liver-directed therapies are available for patients, ranging from surgery and liver transplantation to intra-arterial therapies, thermal ablation procedures, systemic therapies, and radiation treatments. With the introduction of hypofractionated irradiation, particle therapy, and radioembolization, there is growing interest in the use of radiation as a treatment for liver malignancies. This book examines basic principles of the management of liver tumors. The evolving roles of x-ray and particle therapies as well as radioembolization in the treatment of liver tumors is the main focus. A theme of multidisciplinary management is also emphasized, as surgical, interventional and systemic therapies are reviewed. A unique resource that discusses the role of radiation treatment in the context of other liver-directed therapies, Radiation Therapy for Liver Tumors is of broad interest to radiation oncologists, surgeons, hepatologists, medical oncologists, and radiologists.

Colorectal Cancer Liver Metastases

Colorectal Cancer Liver Metastases
Author: Mauro Monteiro Correia
Publisher: Springer Nature
Total Pages: 597
Release: 2019-12-28
Genre: Medical
ISBN: 3030254860

Colorectal cancer is the third most commonly diagnosed condition in oncology, affecting around 1.23 million individuals per year, according to recent statistics. Of these patients, about 50% will develop liver metastases and approximately 20% will present a stage IV disease at diagnosis. These statistics make colorectal liver metastases (CLM) an issue of major importance in current oncology. The area of CLM is subject to great and continuous advances, as its pathophysiologic mechanisms are better understood and more therapeutic and surgical options are developed. Consequently, all professionals involved with the diagnosis, treatment and follow up of CLM should be kept up to date with the latest advances on the field, to provide high standard medical care to their patients. This book is designed to present the state-of-the-art in CLM management and, in doing so, to review the current evidence on CLM, discussing all important topics in the field. Coverage is broad and comprehensive, encompassing introductory topics (history, definitions, epidemiology, etc.), basic science subjects (molecular biology, genetics, dissemination process, etc.) and practical clinical topics (tumor behavior, diagnosis, drug therapy, radiation therapy, surgery, ablation, multidisciplinary teams, etc.). Although comprehensive on the coverage and selection of topics, each chapter is concise and objective, dissecting topics in a practical and direct format. Evidences and recommendations are included. Chapters display a brief introduction of the common knowledge, go straight to the detailed revision of the most recent years of the literature, and end with practical closing observations. This book is a tool for professionals (general and cancer surgeons, HPB surgeons, clinical oncologists, gastroenterologists and medical residents) and interns who search for a qualified and reader friendly revision on topics concerning Colorectal Cancer Liver Metastases.

Stereotactic Body Radiation Therapy

Stereotactic Body Radiation Therapy
Author: Yasushi Nagata
Publisher: Springer
Total Pages: 246
Release: 2015-08-06
Genre: Medical
ISBN: 4431548831

This book serves as a practical guide for the use of stereotactic body radiation therapy in clinics. On the basis of more than 10 years of clinical experience with lung cancer, liver cancer and other cancers, a remarkable volume of knowledge has been accumulated. At the same time, great progress in techniques has been achieved. Various new fixing apparatuses, new respiratory regulation techniques, new dose fractionation schedules and new image-guided radiation therapy machines have been developed. This book reviews the history of those developments and reports on various types of toxicities. Review of recent clinical studies is also included. The authors were key members of the JCOG 0403 clinical trials on stereotactic body radiation therapy (SBRT) for both inoperable and operableT1N0M0 primary lung cancer. Readers will learn of the superior outcomes obtained with SBRT for lung cancer and other cancers in terms of local control and toxicities. With its practical focus, this book will benefit radiation oncologists, medical physicists, medical dosimetrists, radiation therapists and senior nurses as well as medical oncologists and surgical oncologists who are interested in radiotherapy.