Theological thought has long been focused on the meaning to be found in our existence, but it has tended to neglect what it might offer to those seeking how to prolong and improve our physical existence in this world. In conversation with twentieth-century materialist art and thought, this book presents a radical theology that engages directly with the political and ecological issues of our time. The book introduces a new thinker to the theological sphere, Russian avantgarde artist Liubov Popova (1889–1924). She was a woman acknowledged for her artistic and intellectual talent and yet is never discussed in relation to the twentieth-century thinkers with whom her ideas have obvious connections. Popova’s art and thought are discussed together with thinkers like Walter Benjamin, Donna Haraway, Gilles Deleuze and Paul Tillich, along with ecotheological and theopolitical perspectives. Inspired by the activist creativity of avantgarde art, the book’s final chapter, playfully yet with deadly seriousness, presents a manifesto for radical theology today. This is a work of theological activism that demonstrates the benefit of allowing new voices into the conversations around art, spirituality and our planet. As such, it will be of keen interest to academics in Theology, Religion and the Arts and the Philosophy of Religion.