| Author | : Klara Valko |
| Publisher | : Elsevier |
| Total Pages | : 613 |
| Release | : 2000-10-13 |
| Genre | : Science |
| ISBN | : 0080541097 |
Separation Methods in Drug Synthesis and Purification
Separation Technologies for the Industries of the Future
| Author | : Panel on Separation Technology for Industrial Reuse and Recycling |
| Publisher | : National Academies Press |
| Total Pages | : 128 |
| Release | : 1999-01-22 |
| Genre | : Technology & Engineering |
| ISBN | : 0309592828 |
Separation processesor processes that use physical, chemical, or electrical forces to isolate or concentrate selected constituents of a mixtureare essential to the chemical, petroleum refining, and materials processing industries. In this volume, an expert panel reviews the separation process needs of seven industries and identifies technologies that hold promise for meeting these needs, as well as key technologies that could enable separations. In addition, the book recommends criteria for the selection of separations research projects for the Department of Energy's Office of Industrial Technology.
Beyond the Molecular Frontier
| Author | : National Research Council |
| Publisher | : National Academies Press |
| Total Pages | : 238 |
| Release | : 2003-03-19 |
| Genre | : Science |
| ISBN | : 0309168392 |
Chemistry and chemical engineering have changed significantly in the last decade. They have broadened their scopeâ€"into biology, nanotechnology, materials science, computation, and advanced methods of process systems engineering and controlâ€"so much that the programs in most chemistry and chemical engineering departments now barely resemble the classical notion of chemistry. Beyond the Molecular Frontier brings together research, discovery, and invention across the entire spectrum of the chemical sciencesâ€"from fundamental, molecular-level chemistry to large-scale chemical processing technology. This reflects the way the field has evolved, the synergy at universities between research and education in chemistry and chemical engineering, and the way chemists and chemical engineers work together in industry. The astonishing developments in science and engineering during the 20th century have made it possible to dream of new goals that might previously have been considered unthinkable. This book identifies the key opportunities and challenges for the chemical sciences, from basic research to societal needs and from terrorism defense to environmental protection, and it looks at the ways in which chemists and chemical engineers can work together to contribute to an improved future.
Separation Methods in Drug Synthesis and Purification
| Author | : Klara Valko |
| Publisher | : Elsevier |
| Total Pages | : 790 |
| Release | : 2020-06-19 |
| Genre | : Science |
| ISBN | : 0444640711 |
Separation Methods in Drug Synthesis and Purification, Second Edition, Volume Eight, provides an updated on the analytical techniques used in drug synthesis and purification. Unlike other books on either separation science or drug synthesis, this volume combines the two to explain the basic principles and comparisons of each separation technique. New sections to this volume include enantiomer separation using capillary electrophoresis (CE) and capillary electro- chromatography, the computer simulation of chromatographic separation for accelerating method development, the application of chromatography and capillary electrophoresis used as surrogates for biological processes, and new developments in the established techniques of chromatography and preparative methods. - Features descriptions and applications of all separation methods used in the pharmaceutical industry - Written by the leading scientists in their respective fields, providing solutions for a wide range of industrial separation problems encountered within the pharmaceutical industry - Thoroughly updated with brand new separation science techniques and the latest developments in the established techniques of chromatography
Chiral Separation Methods for Pharmaceutical and Biotechnological Products
| Author | : Satinder Ahuja |
| Publisher | : John Wiley & Sons |
| Total Pages | : 474 |
| Release | : 2011-03-31 |
| Genre | : Science |
| ISBN | : 1118097750 |
Discusses chiral separations and offers guidance for selecting the optimum method for desired results Chiral separations represent the most intriguing and, by some measures, most difficultseparations of chemical compounds. This book provides researchers and students an under-standing of chiral separations and offers a convenient route to selecting the best separation method, saving considerable time and cost in product development. Considering chiral separations in the biotechnological and pharmaceutical industries, as well as for food applications, Dr. Ahuja provides insights into a broad range of topics. Opening with a broad overview of chiral separations, regulatory considerations in drug product development, and basic issues in method development, the book: Covers a variety of modern methods such as gas chromatography, high performance liquid chromatography, supercritical fluid chromatography, and capillary electrophoresis Deals with the impact of chirality on the biological activity of small and large molecules Provides detailed information on useful chiral stationary phases (CSPs) for HPLC Includes handy information on selection of an appropriate CSP, including mechanistic studies Offers strategies for fast method development with HPLC, SFC, and CE Discusses preparatory methods utilized in the pharmaceutical industry With in-depth discussions of the current state of the field as well as suggestions to assist future developments, Chiral Separation Methods for Pharmaceutical and Biotechnological Products is an essential text for laboratory investigators, managers, and regulators who are involved in chiral separations in the pharmaceutical industry, as well as students preparing for careers in these fields.
A Research Agenda for Transforming Separation Science
| Author | : National Academies of Sciences, Engineering, and Medicine |
| Publisher | : National Academies Press |
| Total Pages | : 115 |
| Release | : 2019-10-30 |
| Genre | : Science |
| ISBN | : 0309491703 |
Separation science plays a critical role in maintaining our standard of living and quality of life. Many industrial processes and general necessities such as chemicals, medicines, clean water, safe food, and energy sources rely on chemical separations. However, the process of chemical separations is often overlooked during product development and this has led to inefficiency, unnecessary waste, and lack of consensus among chemists and engineers. A reevaluation of system design, establishment of standards, and an increased focus on the advancement of separation science are imperative in supporting increased efficiency, continued U.S. manufacturing competitiveness, and public welfare. A Research Agenda for Transforming Separation Science explores developments in the industry since the 1987 National Academies report, Separation and Purification: Critical Needs and Opportunities. Many needs stated in the original report remain today, in addition to a variety of new challenges due to improved detection limits, advances in medicine, and a recent emphasis on sustainability and environmental stewardship. This report examines emerging chemical separation technologies, relevant developments in intersecting disciplines, and gaps in existing research, and provides recommendations for the application of improved separation science technologies and processes. This research serves as a foundation for transforming separation science, which could reduce global energy use, improve human and environmental health, and advance more efficient practices in various industries.
Comprehensive Organic Chemistry Experiments for the Laboratory Classroom
| Author | : Carlos A. M. Afonso |
| Publisher | : Royal Society of Chemistry |
| Total Pages | : 976 |
| Release | : 2016-12-16 |
| Genre | : Science |
| ISBN | : 1849739633 |
This expansive and practical textbook contains organic chemistry experiments for teaching in the laboratory at the undergraduate level covering a range of functional group transformations and key organic reactions.The editorial team have collected contributions from around the world and standardized them for publication. Each experiment will explore a modern chemistry scenario, such as: sustainable chemistry; application in the pharmaceutical industry; catalysis and material sciences, to name a few. All the experiments will be complemented with a set of questions to challenge the students and a section for the instructors, concerning the results obtained and advice on getting the best outcome from the experiment. A section covering practical aspects with tips and advice for the instructors, together with the results obtained in the laboratory by students, has been compiled for each experiment. Targeted at professors and lecturers in chemistry, this useful text will provide up to date experiments putting the science into context for the students.
Purification of Laboratory Chemicals
| Author | : W.L.F. Armarego |
| Publisher | : Elsevier |
| Total Pages | : 627 |
| Release | : 2003-03-07 |
| Genre | : Technology & Engineering |
| ISBN | : 0080515460 |
Now in its fifth edition, the book has been updated to include more detailed descriptions of new or more commonly used techniques since the last edition as well as remove those that are no longer used, procedures which have been developed recently, ionization constants (pKa values) and also more detail about the trivial names of compounds.In addition to having two general chapters on purification procedures, this book provides details of the physical properties and purification procedures, taken from literature, of a very extensive number of organic, inorganic and biochemical compounds which are commercially available. This is the only complete source that covers the purification of laboratory chemicals that are commercially available in this manner and format.* Complete update of this valuable, well-known reference* Provides purification procedures of commercially available chemicals and biochemicals* Includes an extremely useful compilation of ionisation constants
