Higher Education Institutions (HEIs) around the world are being pressured to become more entrepreneurial. However, the concept of an entrepreneurial university has remained elusive, including ideas that range from supporting students and staff with new ventures to encouraging partnerships between academics and entrepreneurs. New research is needed on strategies and practices that can be implemented by universities in order to become more innovative and supportive. Strategies for the Creation and Maintenance of Entrepreneurial Universities uses findings from a major EU-funded five country project (THEI2.0) focused on enhancing the implementation and impact of the EU-OECD’s HEInnovate tool to offer valuable strategies to help universities become more entrepreneurial, especially in the current COVID-19 and post-COVID-19 environments. This book’s core value lies in the fact that it draws on real experiences and practices of those in this field, articulates key takeaway messages, and suggests potential strategies and actions to create impact. Covering topics such as campus incubation, policy strategies, and regional development, this book acts as an essential resource for senior academic leaders, academic managers, entrepreneurship/entrepreneurial educators, incubation center managers, technology transfer managers, researchers, students, and administrators seeking to make their university more entrepreneurial, maintain their entrepreneurial status, critically reflect on their current level of entrepreneurialism, explore new opportunities to enhance their entrepreneurial reputation, or implement strategies to consolidate their entrepreneurial endeavors within the current challenging environment.