Sudden Death in the Young

by Roger W. Byard

Author	: Roger W. Byard
Publisher	: Cambridge University Press
Total Pages	: 701
Release	: 2010-09-16
Genre	: Medical
ISBN	: 1139855514

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Determining the cause of death in children and young adults can pose considerable challenges. Professor Byard provides for the first time a complete overview of pathological aspects of sudden death in the young, from before birth to middle adult life. Highly illustrated with more than 800 colour figures, this third edition contains new sections on sexual abuse, pregnancy-related deaths and rare natural diseases, as well as expanded coverage of unexpected death in young adults up to the age of 30 years. Chapters are organised by systems and cover all aspects of natural death, as well as accidents, suicides and homicides. Supported by extensive referencing and numerous tables, the book can also be used as a practical autopsy manual. An encyclopaedic overview and analysis of sudden death in the young, this is a key text for pediatric and forensic pathologists, pediatricians, and lawyers and physicians involved in medicolegal cases.

Strategies to Improve Cardiac Arrest Survival

by Institute of Medicine

Author	: Institute of Medicine
Publisher	: National Academies Press
Total Pages	: 291
Release	: 2015-09-29
Genre	: Medical
ISBN	: 030937202X

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Cardiac arrest can strike a seemingly healthy individual of any age, race, ethnicity, or gender at any time in any location, often without warning. Cardiac arrest is the third leading cause of death in the United States, following cancer and heart disease. Four out of five cardiac arrests occur in the home, and more than 90 percent of individuals with cardiac arrest die before reaching the hospital. First and foremost, cardiac arrest treatment is a community issue - local resources and personnel must provide appropriate, high-quality care to save the life of a community member. Time between onset of arrest and provision of care is fundamental, and shortening this time is one of the best ways to reduce the risk of death and disability from cardiac arrest. Specific actions can be implemented now to decrease this time, and recent advances in science could lead to new discoveries in the causes of, and treatments for, cardiac arrest. However, specific barriers must first be addressed. Strategies to Improve Cardiac Arrest Survival examines the complete system of response to cardiac arrest in the United States and identifies opportunities within existing and new treatments, strategies, and research that promise to improve the survival and recovery of patients. The recommendations of Strategies to Improve Cardiac Arrest Survival provide high-priority actions to advance the field as a whole. This report will help citizens, government agencies, and private industry to improve health outcomes from sudden cardiac arrest across the United States.

SIDS Sudden Infant and Early Childhood Death

by Roger W. Byard

Author	: Roger W. Byard
Publisher	:
Total Pages	: 844
Release	: 2018-04
Genre	: Medical
ISBN	: 9781925261677

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This volume covers aspects of sudden infant and early childhood death, ranging from issues with parental grief, to the most recent theories of brainstem neurotransmitters. It also deals with the changes that have occurred over time with the definitions of SIDS (sudden infant death syndrome), SUDI (sudden unexpected death in infancy) and SUDIC (sudden unexpected death in childhood). The text will be indispensable for SIDS researchers, SIDS organisations, paediatric pathologists, forensic pathologists, paediatricians and families, in addition to residents in training programs that involve paediatrics. It will also be of use to other physicians, lawyers and law enforcement officials who deal with these cases, and should be a useful addition to all medical examiner/forensic, paediatric and pathology departments, hospital and university libraries on a global scale. Given the marked changes that have occurred in the epidemiology and understanding of SIDS and sudden death in the very young over the past decade, a text such as this is very timely and is also urgently needed.

Is Daddy Coming Back in a Minute?

by Elke Barber

Author	: Elke Barber
Publisher	: Jessica Kingsley Publishers
Total Pages	: 39
Release	: 2016-07-21
Genre	: Juvenile Nonfiction
ISBN	: 1784503711

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When we were on a No Girls Allowed! holiday, my daddy's heart stopped beating and I had to find help all by myself. He was very badly broken. Not even the ambulance people could help him... This honest, sensitive and beautifully illustrated picture book is designed to help explain the concept of death to children aged 3+. Written in Alex's own words, it is based on the real-life conversations that Elke Barber had with her then three-year-old son, Alex, after the sudden death of his father. The book provides reassurance and understanding to readers through clear and honest answers to the difficult questions that can follow the death of a loved one, and carries the invaluable message that it is okay to be sad, but it is okay to be happy, too.

Pathology of Heart Disease in the Fetus, Infant and Child

by Michael T. Ashworth

Author	: Michael T. Ashworth
Publisher	: Cambridge University Press
Total Pages	: 361
Release	: 2019-08-22
Genre	: Family & Relationships
ISBN	: 1107116287

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Clearly presents the pathology of heart disease from fetus to adolescence, integrating histology and macroscopy with effects of treatment.

Molecular Cardiology

by Zhongjie Sun

Author	: Zhongjie Sun
Publisher	: Springer Science & Business Media
Total Pages	: 410
Release	: 2008-02-01
Genre	: Medical
ISBN	: 159259879X

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The aim of Molecular Cardiology: Methods and Protocols is to document state-of-the-art molecular and genetic techniques in the area of cardiology. These modern approaches enable researchers to readily study heart diseases at the molecular level and will promote the development of new therapeutic str- egies. Methods for genetic dissection, signal transduction, and microarray analysis are excellent tools for the study of the molecular mechanisms of cardiovascular diseases. Protocols for transgenesis take advantage of recent advances in many areas of molecular and cell biology. Transgenic models of heart diseases (cardiac hypertrophy, cardiac dysfunction, and so on. ) are powerful tools for the study of heart disease pathogenesis. Methods for gene transfer to heart tissue using viral and nonviral vectors form the basis of gene therapy for heart diseases. Heart-specific promoters containing a hypox- inducible cardioprotective gene switch are key for protection of the heart from ischemia. Gene and stem cell therapies open novel and exciting avenues for the prevention and treatment of heart diseases. Molecular Cardiology: Methods and Protocols consists of 26 chapters de- ing with various aspects of molecular cardiology, including gene transfer and gene therapy for cardiovascular disease, stem cell therapy for cardiovascular disease, gene analysis in the injured and hypertrophied heart, and transgenesis in cardiovascular research. This book provides step-by-step methods for the successful completion of experimental procedures, and would be useful for both experienced and new investigators in the field of molecular cardiology.

Sudden Death in Infancy, Childhood and Adolescence

by Roger W. Byard

Author	: Roger W. Byard
Publisher	: Cambridge University Press
Total Pages	: 674
Release	: 2004-01-08
Genre	: Family & Relationships
ISBN	: 9780521825825

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This unique, comprehensive survey of virtually all aspects of sudden death in infants and childhood will be an essential source of reference for pathologists, clinicians and lawyers who deal with such cases. Individual sections deal in detail with deaths due to inflicted and non-inflicted injuries and to natural diseases. This new edition includes 1200 new references, 300 new illustrations and an extensively revised chapter on sudden infant death syndrome. The intentional injury chapter has additional material on head trauma, the biomechanics of injury, neonaticide, suicide and subtle and unusual trauma. The chapter on non-intentional injury has also been expanded to more accurately reflect its importance as a cause of death. Deaths in the first week of life are also covered. This new edition also covers the full range of natural causes of death, and their pathological investigation undertaken in light of advances in our understanding of genetic susceptibility and pathophysiology.

Clinical Cardiogenetics

by H.F. Baars

Author	: H.F. Baars
Publisher	: Springer Science & Business Media
Total Pages	: 453
Release	: 2010-12-25
Genre	: Medical
ISBN	: 1849964718

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Clinical management and signs are the focus of this practical cardiogenetic reference for those who are involved in the care for cardiac patients with a genetic disease. With detailed discussion of the basic science of cardiogenetics in order to assist in the clinical understanding of the topic. The genetic causes of various cardiovascular diseases are explained in a concise clinical way that reinforces the current management doctrine in a practical manner. The authors will cover the principles of molecular genetics in general but also specific to cardiac diseases. They will discuss the etiology, pathogenesis, pathophysiology, clinical presentation, clinical diagnosis, molecular diagnosis and treatment of each cardiogenetic disease separately. Therapy advice, ICD indications, indications for and manner of further family investigation will all be covered, while each chapter will also contain take-home messages to reinforce the key points. The chapters reviewing the different diseases will each contain a table describing the genes involved in each. Each chapter will also contain specific illustrations, cumulatively giving a complete, practical review of each cardiogenetic disease separately. Special emphasis will be given to advice on how to diagnose and manage cardiogenetic diseases in clinical practice, which genes should be investigated and why, and the pros and cons of genetic testing. Guidelines for investigation in families with sudden cardiac death at young age will also be included. This book will be written for the general cardiologist and the clinical geneticist who is involved in cardiac patients and will provide answers to question such as: Which genes are involved and which mutations? What is the effect of the mutation at cellular level? Which genes should be tested and why? What is the value of a molecular diagnosis? Does it influence therapy? When should the first degree relatives be tested and in which way?

Sudden Death

by Jiashin Wu

Author	: Jiashin Wu
Publisher	: Nova Science Publishers
Total Pages	: 0
Release	: 2013
Genre	: Cardiac arrest
ISBN	: 9781626188259

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This book dedicates the first seven chapters to cardiac electrophysiological dysfunction that can lead to ventricular fibrillation and sudden death. The next six chapters expand the topics of sudden death to other causes. Brugada Syndrome is the top cause of non-traumatic sudden death in young males of Southeastern Asian and southern European origins. Chapters One and Two review extensively the history and current status, mechanisms of arrhythmias, and related gene mutations in Brugada Syndrome, and discuss gaps in the current knowledge. Chapter Three presents clinical studies on the A1180V and R1193Q mutations of the cardiac sodium channel gene, SCN5A. The authors identified R1193Q mutation in 12.8%-16% of a healthy Chinese population. This result prompted the question of whether SCN5A mutations are still the top genetic bases of Brugada and long QT syndromes. Chapters Four, Five and Seven discuss the pathophysiology causes, risk factors, predictors, prevention, and possible therapeutical strategies of sudden cardiac death. Chapter Six reviews the scope and causes of sudden cardiac death in athletics.Chapter Seven is dedicated to the roles of electrical cardiac systole in sudden death. Chapter Eight reviews sudden death related to cardiac and brain tumours, pulmonary tumour embolism, asphyxia, massive exsanguinations, and their pathophysiology. Chapter Nine summarises the pathophysiology of sudden death caused by myocardial tuberculosis. Chapter Ten introduces pathophysiology of sudden death during hot baths in deep bathtubs, which occurs frequently in elderly people in Japan. Chapter Eleven discusses air pollution as a trigger of sudden death. Chapter Twelve presents biochemical, cytological and histopathological examination of sudden unexpected death in infancy. The last chapter of the book, Chapter Thirteen, reviews post-mortem cardiac markers in different body fluids and their application in forensic pathology diagnosis of sudden cardiac death. In combination, these chapters cover a broad range of topics about sudden death.