The Black Box of Biology

The Black Box of Biology
Author: Michel Morange
Publisher: Harvard University Press
Total Pages: 529
Release: 2020-06-09
Genre: Science
ISBN: 0674281365

In this masterful account, a historian of science surveys the molecular biology revolution, its origin and continuing impact. Since the 1930s, a molecular vision has been transforming biology. Michel Morange provides an incisive and overarching history of this transformation, from the early attempts to explain organisms by the structure of their chemical components, to the birth and consolidation of genetics, to the latest technologies and discoveries enabled by the new science of life. Morange revisits A History of Molecular Biology and offers new insights from the past twenty years into his analysis. The Black Box of Biology shows that what led to the incredible transformation of biology was not a simple accumulation of new results, but the molecularization of a large part of biology. In fact, Morange argues, the greatest biological achievements of the past few decades should still be understood within the molecular paradigm. What has happened is not the displacement of molecular biology by other techniques and avenues of research, but rather the fusion of molecular principles and concepts with those of other disciplines, including genetics, physics, structural chemistry, and computational biology. This has produced decisive changes, including the discoveries of regulatory RNAs, the development of massive scientific programs such as human genome sequencing, and the emergence of synthetic biology, systems biology, and epigenetics. Original, persuasive, and breathtaking in its scope, The Black Box of Biology sets a new standard for the history of the ongoing molecular revolution.

Darwin's Black Box

Darwin's Black Box
Author: Michael J. Behe
Publisher: Simon and Schuster
Total Pages: 353
Release: 1996
Genre: Evolution (Biology)
ISBN: 9780684827544

Behe argues that the complexity of cellular biochemistry argues against Darwin's gradual evolution.

A History of Molecular Biology

A History of Molecular Biology
Author: Michel Morange
Publisher: Harvard University Press
Total Pages: 350
Release: 2000
Genre: History
ISBN: 9780674001695

Every day it seems the media focus on yet another new development in biology--gene therapy, the human genome project, the creation of new varieties of animals and plants through genetic engineering. These possibilities have all emanated from molecular biology. A History of Molecular Biology is a complete but compact account for a general readership of the history of this revolution. Michel Morange, himself a molecular biologist, takes us from the turn-of-the-century convergence of molecular biology's two progenitors, genetics and biochemistry, to the perfection of gene splicing and cloning techniques in the 1980s. Drawing on the important work of American, English, and French historians of science, Morange describes the major discoveries--the double helix, messenger RNA, oncogenes, DNA polymerase--but also explains how and why these breakthroughs took place. The book is enlivened by mini-biographies of the founders of molecular biology: Delbrück, Watson and Crick, Monod and Jacob, Nirenberg. This ambitious history covers the story of the transformation of biology over the last one hundred years; the transformation of disciplines: biochemistry, genetics, embryology, and evolutionary biology; and, finally, the emergence of the biotechnology industry. An important contribution to the history of science, A History of Molecular Biology will also be valued by general readers for its clear explanations of the theory and practice of molecular biology today. Molecular biologists themselves will find Morange's historical perspective critical to an understanding of what is at stake in current biological research.

Black Boxes

Black Boxes
Author: Marco J. Nathan
Publisher: Oxford University Press
Total Pages: 313
Release: 2021
Genre: Philosophy
ISBN: 0190095482

Bricks and boxes -- Between Scylla and Charybdis -- Lessons from the history of science -- Placeholders -- Black-boxing 101 -- History of science 'black-boxing style' -- Diet mechanistic philosophy -- Emergence reframed -- The fuel of scientific progress -- Sailing through the strait.

Biological Measures of Human Experience across the Lifespan

Biological Measures of Human Experience across the Lifespan
Author: Lynnette Leidy Sievert
Publisher: Springer
Total Pages: 334
Release: 2016-12-21
Genre: Social Science
ISBN: 3319441035

This volume explores methods used by social scientists and human biologists to understand fundamental aspects of human experience. It is organized by stages of the human lifespan: beginnings, adulthood, and aging. Explored are particular kinds of experiences - including pain, stress, activity levels, sleep quality, memory, and menopausal hot flashes - that have traditionally relied upon self-reports, but are subject to inter-individual differences in self-awareness or culture-based expectations. The volume also examines other ways in which normally “invisible” phenomena can be made visible, such as the caloric content of foods, blood pressure, fecundity, growth, nutritional status, genotypes, and bone health. All of the chapters in this book address the means by which social scientists and human biologists measure subjective and objective experience.

Computational Methods in Systems Biology

Computational Methods in Systems Biology
Author: Vincent Danos
Publisher: Springer
Total Pages: 288
Release: 2005-04-01
Genre: Computers
ISBN: 3540259740

The Computational Methods in Systems Biology (CMSB) workshop series was established in 2003 by Corrado Priami. The purpose of the workshop series is to help catalyze the convergence between computer scientists interested in language design, concurrency theory, software engineering or program verification, and physicists, mathematicians and biologists interested in the systems-level understanding of cellular processes. Systems biology was perceived as being increasingly in search of sophisticated modeling frameworks whether for representing and processing syst- level dynamics or for model analysis, comparison and refinement. One has here a clear-cut case of a must-explore field of application for the formal methods developed in computer science in the last decade. This proceedings consists of papers from the CMSB 2003 workshop. A good third of the 24 papers published here have a distinct formal methods origin; we take this as a confirmation that a synergy is building that will help solidify CMSB as a forum for cross-community exchange, thereby opening new theoretical avenues and making the field less of a potential application and more of a real one. Publication in Springer's new Lecture Notes in Bioinformatics (LNBI) offers particular visibility and impact, which we gratefully acknowledge. Our keynote speakers, Alfonso Valencia and Trey Ideker, gave challenging and somewhat humbling lectures: they made it clear that strong applications to systems biology are still some way ahead. We thank them all the more for accepting the invitation to speak and for the clarity and excitement they brought to the conference.

Biology Made Real

Biology Made Real
Author: Christian Moore-Anderson
Publisher: Christian Moore-Anderson
Total Pages: 246
Release: 2023-04-05
Genre: Education
ISBN:

'This outstanding book... deserves to be very widely read. I hope it makes a major contribution to how school biology is taught.' —Dr Michael J. Reiss, Professor of Science Education, University of London 'This is a book that all teachers, not just biology teachers should read.' —Ben Strathearn-Burrows, Head of Biology, Emanuel School What you'll find inside: —A vision for an integrated and meaningful biology education. —A framework for teaching for meaning-making, which cuts planning time. —Ways of creating a unified narrative across disparate topics. —A taxonomy of understanding that unlocks problem-solving with minimal workload. —Tried and tested examples from mixed-attainment biology classrooms. Introduction I've been motivated to discover what biology is to us as humans. What it means to understand biology, and how I could make it meaningful for my students. I've read as much as I could and reflected, I've discussed and listened, I've taught and observed. While it doesn't cover all aspects of biology education, this book is about sharing what I've learnt on my journey of synthesising and trialling ideas with my secondary-school mixed-attainment biology classes. 'Not only is this book likely to change how you teach biology but also how you perceive yourself within the living world.' —Dr Alex Sinclair, Institute of Education, St Mary's University, Twickenham Chapter 1: Meaningful biology relates principally to organisms: This sets the scene for the whole book. It brings together many threads to define what I see as most meaningful to secondary biology students. And therefore what we could do about it when designing our lessons & curricula and thinking about how students progress through their biology education. Planning for meaning-making has vastly enhanced interest and motivation to learn in my classroom. Chapters 2 & 3: Teaching for meaning using variation theory: Next I introduce a powerful—relatively unknown and often misunderstood—pedagogical theory. Variation theory. In these chapters I set out to show how useful it is—and easy to use—in the secondary biology classroom, with many examples. Chapter 4: How to integrate organisms, ecology & evolution: Now I pull together the previous chapters to present a new framework for teaching for meaning-making that cuts planning time & focuses on biology. 'An excellent text demanding we think not just about what we teach but also why and how.’ —Dr Paul Ganderton, Consultant and researcher Chapter 5: Concepts of the organism that unite a biology course: Here I discuss two concepts that I think can unify all the topics on the curriculum. 1. Seeing biology through thermodynamic systems lens and, 2. Seeing biology through an ecological-evolutionary lens via the concept of life strategies. I lay out the reasons why and discuss how I've introduced these ideas with students. Chapter 6: Teaching systems thinking to help students see interconnectedness: This chapter is dedicated to systems thinking. Firstly I show how stock and flow diagrams are very useful for the biology classroom and give examples. Next, I introduce a new taxonomy of understanding biological systems. Chapter 7: Establishing a thinking classroom: This chapter is focused on the whys and hows of embedding the taxonomy into my biology curricula. I give examples of how I use it and examples of my students answers from lower and upper secondary courses. Chapter 8: Navigating classroom and biological complexity: This chapter rounds up the book by considering the complexity of our subject and the classroom. ‘Biology Made Real comes with an education health warning—be prepared to have your beliefs challenged.' —Dr Alex Sinclair

Biology and Political Science

Biology and Political Science
Author: Robert Blank
Publisher: Routledge
Total Pages: 192
Release: 2002-03-11
Genre: Political Science
ISBN: 1134629060

This book demonstrates the increasing interest of some social scientists in the theories, research and findings of life sciences in building a more interdisciplinary approach to the study of politics. It discusses the development of biopolitics as an academic perspective within political science, reviews the growing literature in the field and presents a coherent view of biopolitics as a framework for structuring inquiry across the current subfields of political science.

The Biology of Caves and Other Subterranean Habitats

The Biology of Caves and Other Subterranean Habitats
Author: David C. Culver
Publisher: Oxford University Press
Total Pages: 336
Release: 2019-04-01
Genre: Science
ISBN: 0192552767

The second edition of this widely cited textbook continues to provide a concise but comprehensive introduction to cave and subterranean biology, describing this fascinating habitat and its biodiversity. It covers a range of biological processes including ecosystem function, evolution and adaptation, community ecology, biogeography, and conservation. The authors draw on a global range of examples and case studies from both caves and non-cave subterranean habitats. One of the barriers to the study of subterranean biology has been the extraordinarily large number of specialized terms used by researchers; the authors explain these terms clearly and minimize the number that they use. This new edition retains the same 10 chapter structure of the original, but the content has been thoroughly revised and updated throughout to reflect the huge increase in publications concerning subterranean biology over the last decade.