The Microbiome and the Brain

The Microbiome and the Brain
Author: David Perlmutter
Publisher: CRC Press
Total Pages: 182
Release: 2019-12-06
Genre: Medical
ISBN: 1351235680

Brain related disorders are among the most challenging health issues of our time. The development of effective therapeutic and preventive strategies for these disorders relies on a comprehensive understanding of the underlying causative mechanisms. And, until recently, these mechanisms have remained somewhat elusive. The newly discovered pivotal role of the intestinal microbiome in brain health, functionality, and resistance to disease is revolutionizing neuroscience. The Microbiome and the Brain, through the contributions of some of the most forward thinking researchers and clinicians in the field, comprehensively reveals the leading edge of our understanding of the fundamental role of gut microbes and their metabolites in a wide array of seemingly diverse brain issues including Alzheimer’s disease, autism, multiple sclerosis, and mood disorders. In addition, mechanisms defining these relationships are explored along with a presentation of the state-of-the-art as it relates to interpretation of relevant laboratory assessments. Finally, novel therapeutic opportunities, derived from this exciting science are presented. Readers will learn: The highly validated relationship between alterations of gut microbes and their metabolites, and risk for Alzheimer’s disease. The important link between autism and intestinal dysbiosis. Appropriate interpretation of available laboratory assessments of the intestinal microbiome. The potential role of fecal microbial transplant in neurological diseases. The influence of diet and other lifestyle choices on the microbiome as it relates to brain health and functionality.

Gut-brain Connection, Myth Or Reality?: Role Of The Microbiome In Health And Diseases

Gut-brain Connection, Myth Or Reality?: Role Of The Microbiome In Health And Diseases
Author: Adrien A Eshraghi
Publisher: World Scientific
Total Pages: 396
Release: 2021-11-03
Genre: Science
ISBN: 9811221162

In this book the recent advancements in understanding the gut-brain interaction as well as gut microbiome and how this interaction plays a vital role in human health and disease are discussed. Each chapter gives an analysis of questions, research directions, and methods within the field of gut-brain axis. The readers will benefit from the latest knowledge about our understanding about how gut-brain axis and modulation of gut microbiome determines predisposition to neurological disorders. The multidisciplinary book is essential reading for anyone interested in the field of gut-brain axis and gut microbiome: from undergraduates to graduate students as well as scientists and physicians having an interest in the new exciting field of gut microbiome and its relationship with brain function.

Microbial Endocrinology: The Microbiota-Gut-Brain Axis in Health and Disease

Microbial Endocrinology: The Microbiota-Gut-Brain Axis in Health and Disease
Author: Mark Lyte
Publisher: Springer
Total Pages: 440
Release: 2014-07-05
Genre: Science
ISBN: 1493908979

The field of microbial endocrinology is expressly devoted to understanding the mechanisms by which the microbiota (bacteria within the microbiome) interact with the host (“us”). This interaction is a two-way street and the driving force that governs these interactions are the neuroendocrine products of both the host and the microbiota. Chapters include neuroendocrine hormone-induced changes in gene expression and microbial endocrinology and probiotics. This is the first in a series of books dedicated to understanding how bi-directional communication between host and bacteria represents the cutting edge of translational medical research, and hopefully identifies new ways to understand the mechanisms that determine health and disease.​

The Gut-Brain Axis

The Gut-Brain Axis
Author: Niall Hyland
Publisher: Academic Press
Total Pages: 512
Release: 2016-05-13
Genre: Medical
ISBN: 0128025441

The Gut-Brain Axis: Dietary, Probiotic, and Prebiotic Interventions on the Microbiota examines the potential for microbial manipulation as a therapeutic avenue in central nervous system disorders in which an altered microbiota has been implicated, and explores the mechanisms, sometimes common, by which the microbiota may contribute to such disorders. - Focuses on specific areas in which the microbiota has been implicated in gut-brain communication - Examines common mechanisms and pathways by which the microbiota may influence brain and behavior - Identifies novel therapeutic strategies targeted toward the microbiota in the management of brain activity and behavior

The Mind-Gut Connection

The Mind-Gut Connection
Author: Emeran Mayer
Publisher: HarperCollins
Total Pages: 354
Release: 2018-06-05
Genre: Psychology
ISBN: 0062846825

Cutting-edge neuroscience combines with the latest discoveries on the human microbiome to inform this practical guide that proves once and for all the inextricable, biological link between mind and body. We have all experienced the connection between our mind and our gut—the decision we made because it “felt right;” the butterflies in our stomach before a big meeting; the anxious stomach rumbling when we’re stressed out. While the dialogue between the gut and the brain has been recognized by ancient healing traditions, including Aryuvedic and Chinese medicine, Western medicine has failed to appreciate the complexity of how the brain, gut, and more recently, the microbiome—the microorganisms that live inside us—communicate with one another. In The Mind-Gut Connection, Dr. Emeran Mayer, Executive Director of the UCLA Center for Neurobiology of Stress, offers a revolutionary look at this developing science, teaching us how to harness the power of the mind-gut connection to take charge of our health. The Mind-Gut Connection, shows how to keep the communication brain-gut communication clear and balanced to: • Heal the gut by focusing on a plant-based diet • Balance the microbiome by consuming fermented foods and probiotics, fasting, and cutting out sugar and processed foods • Promote weight loss by detoxifying and creating a healthy digestion and maximum nutrient absorption • Boost immunity and prevent the onset of neurological diseases such as Parkinson’s and Alzheimer’s • Generate a happier mindset and reduce fatigue, moodiness, anxiety, and depression • Prevent and heal GI disorders such as leaky gut syndrome; food sensitivities and allergies; and IBS; as well as digestive discomfort such as heartburn and bloating • And much more. Supplemental enhancement PDF accompanies the audiobook.

The Microbiome and Neurotoxicity

The Microbiome and Neurotoxicity
Author:
Publisher: Elsevier
Total Pages: 226
Release: 2024-05-03
Genre: Science
ISBN: 0443215618

Advances in Neurotoxicology, Volume 11 presents interesting chapters written by an international board of authors. Chapters in this new release include Gut microbiota as a mediator on the neurotoxicity of mercury, Relationships between lead-induced learning and memory impairments and gut microbiota disturbance in mice, Utility of zebrafish-based models in understanding molecular mechanisms of neurotoxicity mediated by the gut-brain axis, Alterations of gut microbiota linking environmental exposures to neurotoxicity, Iron Toxicity, Ferroptosis and Microbiota in Parkinson's Disease: Implications for Novel Targets, and Modulation of gut microbiota with probiotics as a strategy to counteract endogenous and exogenous neurotoxicity. - Provides the latest information on Neurotoxicology - Offers outstanding and original reviews on Neurotoxicology - Serves as an indispensable reference for researchers and students alike

An Introduction to the Microbiome in Health and Diseases

An Introduction to the Microbiome in Health and Diseases
Author: Charles Oluwaseun Adetunji
Publisher: Academic Press
Total Pages: 246
Release: 2024-04-22
Genre: Science
ISBN: 0323914721

An Introduction to the Microbiome in Health and Diseases covers the compositional structure and roles of the human microbiome in health and disease. Sections discuss and foundational content, from bench to bedside in microbiology to trigger more in-depth knowledge and provide updated findings on today's hottest topic–the microbiome. The book translates current findings of studies into clinical practice. Other sections give updates on the role of microbiome in health and several diseases, the impact of diet, exercise and gut microbiome, the plant microbiome, non-infectious environmental agents and autoimmunity. - Provides fundamental coverage on the microbiome and its effect on human health and diseases. - Describes procedures for sampling small and larger samples of the microbiome. - Discusses patents, bioproducts, commercialization, and the social, ethical and economic implications of the microbiome.

Microbiome-Gut-Brain Axis

Microbiome-Gut-Brain Axis
Author: R. Z. Sayyed
Publisher: Springer Nature
Total Pages: 443
Release: 2022-01-03
Genre: Science
ISBN: 9811616264

The book highlights the importance of prebiotics, probiotics and synbiotics in the signalling mechanism between gut microbiota and brain, also referred to as the gut-brain axis. A stable gut microbiota is essential for normal gut physiology and overall health, since it assists in proper signalling along the brain–gut axis. The book describes how the cross talks between gut microbiota and brain, not only regulate gastro-intestinal functions but also ensure proper functioning of cognitive behaviour and immunological functions. The various chapters describe probiotic microorganisms that colonize gastrointestinal tract and provide an array of health benefits to the host. It further elaborates about certain non-digestible oligosaccharides (prebiotics) are easily fermented by specialist microbes in the gut, to produce health-promoting metabolites and inhibit the growth of pathogenic bacteria. This book is useful for students, researchers and scientists in the field of microbiology, food science and nutrition. It is also meant for industry experts involved in developing nutraceuticals.