Author | : Dr. Hakim. K. Saboowala |
Publisher | : Dr.Hakim Saboowala |
Total Pages | : 42 |
Release | : 2021-04-22 |
Genre | : Medical |
ISBN | : |
What is Morgellons Disease (MD)? : A poorly understood Dermopathy with Worldwide Distribution. Morgellons disease (MD) is an emerging dermopathy with worldwide distribution. It is characterized by multicolored filaments that lie under, are embedded in, or project from skin. Although MD was initially considered to be a delusional disorder, recent studies have demonstrated that the dermopathy is associated with tickborne infection, that the filaments are composed of keratin and collagen, and that they result from proliferation of keratinocytes and fibroblasts in epithelial tissue. This prompted further investigation into the possibility of a spirochetal etiology for MD to discover if a similar disease process occurred at the cellular level. Spirochetes genetically identified as Borrelia burgdorferi sensu- stricto predominate as the infective agent in most of the Morgellons skin specimens studied so far. Other species of Borrelia have also been detected in skin specimens taken from MD patients. The optimal treatment for MD remains to be determined. An attempt has been made in this Booklet to present a histopathological and molecular evidence of spirochetal infection associated with MD in several published studies using a variety of techniques along with several illustrations for better understanding of the busy medicos at one click! …Dr. H. K. Saboowala. M.B.(Bom) .M.R.S.H.(London)