Managing Discovery in the Life Sciences

Managing Discovery in the Life Sciences
Author: Philip A. Rea
Publisher: Cambridge University Press
Total Pages: 557
Release: 2018-02
Genre: Business & Economics
ISBN: 1107130905

Addresses in roughly equal measure the science and management behind several recent marketable biomedical innovations.

Managing Discovery in the Life Sciences

Managing Discovery in the Life Sciences
Author: Philip A. Rea
Publisher: Cambridge University Press
Total Pages: 557
Release: 2018-02-01
Genre: Political Science
ISBN: 1108675549

In this book, distinguished scholars Philip A. Rea, Mark V. Pauly, and Lawton R. Burns explore the science and management behind marketable biomedical innovations. They look at how the science actually played out through the interplay of personalities, the cultures within and between academic and corporate entities, and the significance of serendipity not as a mysterious phenomenon but one intrinsic to the successes and failures of the experimental approach. With newly aggregated data and case studies, they consider the fundamental economic underpinnings of investor-driven discovery management, not as an obstacle or deficiency as its critics would contend or as something beyond reproach as some of its proponents might claim, but as the only means by which scientists and managers can navigate the unknowable to discover new products and decide how to sell them so as to maximize the likelihood of establishing a sustainable pipeline for still more marketable biomedical innovations.

Semantic Web

Semantic Web
Author: Christopher J. O. Baker
Publisher: Springer Science & Business Media
Total Pages: 449
Release: 2007-04-14
Genre: Science
ISBN: 0387484388

This book introduces advanced semantic web technologies, illustrating their utility and highlighting their implementation in biological, medical, and clinical scenarios. It covers topics ranging from database, ontology, and visualization to semantic web services and workflows. The volume also details the factors impacting on the establishment of the semantic web in life science and the legal challenges that will impact on its proliferation.

Innovative Research in Life Sciences

Innovative Research in Life Sciences
Author: E. Andrew Balas
Publisher: John Wiley & Sons
Total Pages: 416
Release: 2018-11-08
Genre: Medical
ISBN: 1119225884

“I thoroughly enjoyed reading this book as it has taken me on a journey through time, across the globe and through multiple disciplines. Indeed, we need to be thinking about these concepts and applying them every day to do our jobs better.” Farah Magrabi, Macquarie University, Australia “The reader will find intriguing not only the title but also the content of the book. I’m also pleased that public health, and even more specifically epidemiology has an important place in this ambitious discussion.” Elena Andresen, Oregon Health & Science University, USA “This book is very well written and addresses an important topic. It presents many reasons why basic scientists/researchers should establish collaborations and access information outside traditional means and not limit thinking but rather expand such and perhaps develop more innovative and translational research ventures that will advance science and not move it laterally.” Gerald Pepe, Eastern Virginia Medical School, USA “This book gathers logically and presents interestingly (with many examples) the qualities and attitudes a researcher must possess in order to become successful. On the long run, the deep and carefully reexamined research will be the one that lasts.” Zoltán Néda, Babeş-Bolyai University, Romania “I really liked the five pillars delineating the components of humanism in research. This book has made a major contribution to the research ethics literature.” David Fleming, University of Missouri, USA A comprehensive review of the research phase of life sciences from design to discovery with suggestions to improve innovation This vital resource explores the creative processes leading to biomedical innovation, identifies the obstacles and best practices of innovative laboratories, and supports the production of effective science. Innovative Research in Life Sciences draws on lessons from 400 award-winning scientists and research from leading universities. The book explores the innovative process in life sciences and puts the focus on how great ideas are born and become landmark scientific discoveries. The text provides a unique resource for developing professional competencies and applied skills of life sciences researchers. The book examines what happens before the scientific paper is submitted for publication or the innovation becomes legally protected. This phase is the most neglected but most exciting in the process of scientific creativity and innovation. The author identifies twelve competencies of innovative biomedical researchers that described and analyzed. This important resource: Highlights the research phase from design to discovery that precedes innovation disclosure Offers a step by step explanation of how to improve innovation Offers solutions for improving research and innovation productivity in the life sciences Contains a variety of statistical databases and a vast number of stories about individual discoveries Includes a process of published studies and national statistics of biomedical research and reviews the performance of research labs and academic institutions Written for academics and researchers in biomedicine, pharmaceutical science, life sciences, drug discovery, pharmacology, Innovative Research in Life Sciences offers a guide to the creative processes leading to biomedical innovation and identifies the best practices of innovative scientists and laboratories.

Open Source Software in Life Science Research

Open Source Software in Life Science Research
Author: Lee Harland
Publisher: Elsevier
Total Pages: 583
Release: 2012-10-31
Genre: Computers
ISBN: 1908818247

The free/open source approach has grown from a minor activity to become a significant producer of robust, task-orientated software for a wide variety of situations and applications. To life science informatics groups, these systems present an appealing proposition - high quality software at a very attractive price. Open source software in life science research considers how industry and applied research groups have embraced these resources, discussing practical implementations that address real-world business problems.The book is divided into four parts. Part one looks at laboratory data management and chemical informatics, covering software such as Bioclipse, OpenTox, ImageJ and KNIME. In part two, the focus turns to genomics and bioinformatics tools, with chapters examining GenomicsTools and EBI Atlas software, as well as the practicalities of setting up an 'omics' platform and managing large volumes of data. Chapters in part three examine information and knowledge management, covering a range of topics including software for web-based collaboration, open source search and visualisation technologies for scientific business applications, and specific software such as DesignTracker and Utopia Documents. Part four looks at semantic technologies such as Semantic MediaWiki, TripleMap and Chem2Bio2RDF, before part five examines clinical analytics, and validation and regulatory compliance of free/open source software. Finally, the book concludes by looking at future perspectives and the economics and free/open source software in industry. - Discusses a broad range of applications from a variety of sectors - Provides a unique perspective on work normally performed behind closed doors - Highlights the criteria used to compare and assess different approaches to solving problems

Exploring Science

Exploring Science
Author: David Klahr
Publisher: MIT Press
Total Pages: 260
Release: 2000
Genre: Psychology
ISBN: 9780262611763

David Klahr suggests that we now know enough about cognition--and hence about everyday thinking--to advance our understanding of scientific thinking.

The New Players in Life Science Innovation

The New Players in Life Science Innovation
Author: Tomasz F. Mroczkowski
Publisher: Ft Press
Total Pages: 340
Release: 2012
Genre: Business & Economics
ISBN: 9780132119900

The global center of gravity in life sciences innovation is rapidly shifting to emerging economies. In The New Players in Life Science Innovation, Tomasz Mroczkowski explains how China and other new economic powers are rapidly gaining leadership positions, and thoroughly assesses the implications. Mroczkowski discusses the sophisticated innovation strategies and reforms these nations have implemented: approaches that don't rely on market forces alone, and are achieving remarkable success. Next, he previews the emerging global "bio-economy," in which life science discoveries will be applied pervasively in markets ranging from health to fuels. As R&D in the West becomes increasingly costly, Mroczkowski introduces new options for partnering with new players in the field. He thoroughly covers the globalization of clinical trials, showing how it offers opportunities that go far beyond cost reduction, and assessing the unique challenges it presents. Offering examples from China to Dubai to India, he carefully assesses the business models driving today's newest centers of innovation. Readers will find up-to-date coverage of bioparks, technology zones, and emerging clusters, and realistic assessments of global R&D collaboration strategies such as those of Eli Lilly, Merck, Novartis, and IBM. With innovation-driven industries increasingly dominating the global economy, this book's insights are indispensable for every R&D decision-maker and investor.

Managing Scientific Information and Research Data

Managing Scientific Information and Research Data
Author: Svetla Baykoucheva
Publisher: Chandos Publishing
Total Pages: 163
Release: 2015-07-14
Genre: Business & Economics
ISBN: 0081002378

Innovative technologies are changing the way research is performed, preserved, and communicated. Managing Scientific Information and Research Data explores how these technologies are used and provides detailed analysis of the approaches and tools developed to manage scientific information and data. Following an introduction, the book is then divided into 15 chapters discussing the changes in scientific communication; new models of publishing and peer review; ethics in scientific communication; preservation of data; discovery tools; discipline-specific practices of researchers for gathering and using scientific information; academic social networks; bibliographic management tools; information literacy and the information needs of students and researchers; the involvement of academic libraries in eScience and the new opportunities it presents to librarians; and interviews with experts in scientific information and publishing. - Promotes innovative technologies for creating, sharing and managing scientific content - Presents new models of scientific publishing, peer review, and dissemination of information - Serves as a practical guide for researchers, students, and librarians on how to discover, filter, and manage scientific information - Advocates for the adoption of unique author identifiers such as ORCID and ResearcherID - Looks into new tools that make scientific information easy to discover and manage - Shows what eScience is and why it is becoming a priority for academic libraries - Demonstrates how Electronic Laboratory Notebooks can be used to record, store, share, and manage research data - Shows how social media and the new area of Altmetrics increase researchers' visibility and measure attention to their research - Directs to sources for datasets - Provides directions on choosing and using bibliographic management tools - Critically examines the metrics used to evaluate research impact - Aids strategic thinking and informs decision making

Data Integration in the Life Sciences

Data Integration in the Life Sciences
Author: Sarah Cohen-Boulakia
Publisher: Springer Science & Business Media
Total Pages: 221
Release: 2008-06-11
Genre: Computers
ISBN: 3540698272

This book constitutes the refereed proceedings of the 5th International Workshop on Data Integration in the Life Sciences, DILS 2008, held in Evry, France in June 2008. The 18 revised full papers presented together with 3 keynote talks and a tutorial paper were carefully reviewed and selected from 54 submissions. The papers adress all current issues in data integration and data management from the life science point of view and are organized in topical sections on Semantic Web for the life sciences, designing and evaluating architectures to integrate biological data, new architectures and experience on using systems, systems using technologies from the Semantic Web for the life sciences, mining integrated biological data, and new features of major resources for biomolecular data.