Micro- and Nanotechnology in Vaccine Development

by Mariusz Skwarczynski

Author	: Mariusz Skwarczynski
Publisher	: William Andrew
Total Pages	: 462
Release	: 2016-09-20
Genre	: Medical
ISBN	: 0323400299

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This book provides a comprehensive overview of how use of micro- and nanotechnology (MNT) has allowed major new advance in vaccine development research, and the challenges that immunologists face in making further progress. MNT allows the creation of particles that exploit the inherent ability of the human immune system to recognize small particles such as viruses and toxins. In combination with minimal protective epitope design, this permits the creation of immunogenic particles that stimulate a response against the targeted pathogen. The finely tuned response of the human immune system to small particles makes it unsurprising that many of the lead adjuvants and vaccine delivery systems currently under investigation are based on nanoparticles. - Provides a comprehensive and unparalleled overview of the role of micro- and nanotechnology in vaccine development - Allows researchers to quickly familiarize themselves with the broad spectrum of vaccines and how micro- and nanotechnologies are applied to their development - Includes a combination of overview chapters setting out general principles, and focused content dealing with specific vaccines, making it useful to readers from a variety of disciplines

Nanotechnologies in Preventive and Regenerative Medicine

by Vuk Uskokovic

Author	: Vuk Uskokovic
Publisher	: Elsevier
Total Pages	: 618
Release	: 2017-10-30
Genre	: Medical
ISBN	: 0323480640

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Nanotechnologies in Preventative and Regenerative Medicine demonstrates how control at the nanoscale can help achieve earlier diagnoses and create more effective treatments. Chapters take a logical approach, arranging materials by their area of application. Biomaterials are, by convention, divided according to the area of their application, with each chapter outlining current challenges before discussing how nanotechnology and nanomaterials can help solve these challenges This applications-orientated book is a valuable resource for researchers in biomedical science who want to gain a greater understanding on how nanotechnology can help create more effective vaccines and treatments, and to nanomaterials researchers seeking to gain a greater understanding of how these materials are applied in medicine. - Demonstrates how nanotechnology can help achieve more successful diagnoses at an earlier stage - Explains how nanomaterials can be manipulated to create more effective drug treatments - Offers suggestions on how the use of nanotechnology might have future applications to create even more effective treatments

Microneedles for Drug and Vaccine Delivery and Patient Monitoring

by Ryan F. Donnelly

Author	: Ryan F. Donnelly
Publisher	: John Wiley & Sons
Total Pages	: 458
Release	: 2018-06-04
Genre	: Science
ISBN	: 1119305179

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Provides comprehensive coverage of microneedles for delivering and monitoring patient drugs and vaccines Microneedles are an incredibly active research area and have the potential to revolutionize the way many medicines and vaccines are delivered. This comprehensive research book covers the major aspects relating to the use of microneedle arrays in enhancing both transdermal and intradermal drug delivery and provides a sound background to the use of microneedle arrays in enhanced delivery applications. Beginning with a history of the field and the various methods employed to produce microneedles from different materials, Microneedles for Drug and Vaccine Delivery and Patient Monitoring discusses the penetration of the stratum corneum by microneedles and the importance of application method and force and microneedle geometry (height, shape, inter-needle spacing). Transdermal and intradermal delivery research using microneedles is comprehensively and critically reviewed, focusing on the outcomes of in vivo animal and human studies. The book describes the important topics of safety and patient acceptability studies carried out to date. It also covers in detail the growing area for microneedle use in the monitoring of interstitial fluid contents. Finally, it reviews translational and regulatory developments in the microneedles field and describes the work ongoing in industry. The only book currently available on microneedles Filled with tables, graphs, and black and white images (photographs, micrographs) Authored by four experts in pharmaceutics Microneedles for Drug and Vaccine Delivery and Patient Monitoring is an ideal source for researchers in industry and academia working on drug delivery and transdermal delivery in particular, as well as for advanced students in pharmacy and pharmaceutical sciences.

Handbook of Immunological Properties of Engineered Nanomaterials

by Marina Dobrovolskaia

Author	: Marina Dobrovolskaia
Publisher	: World Scientific
Total Pages	: 721
Release	: 2013
Genre	: Medical
ISBN	: 9814390259

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The Handbook of Immunological Properties of Engineered Nanomaterials provides a comprehensive overview of the current literature, methodologies, and translational and regulatory considerations in the field of nanoimmunotoxicology. The main subject is the immunological properties of engineered nanomaterials. Focus areas include interactions between engineered nanomaterials and red blood cells, platelets, endothelial cells, professional phagocytes, T cells, B cells, dendritic cells, complement and coagulation systems, and plasma proteins, with discussions on nanoparticle sterility and sterilization. Each chapter presents a broad literature review of the given focus area, describes protocols and resources available to support research in the individual focus areas, highlights challenges, and outlines unanswered questions and future directions. In addition, the Handbook includes an overview of and serves a guide to the physicochemical characterization of engineered nanomaterials essential to conducting meaningful immunological studies of nanoparticles. Regulations related to immunotoxicity testing of materials prior to their translation into the clinic are also reviewed.The Handbook is written by top experts in the field of nanomedicine, nanotechnology, and translational bionanotechnology, representing academia, government, industry, and consulting organizations, and regulatory agencies. The Handbook is designed to serve as a textbook for students, a practical guide for research laboratories, and an informational resource for scientific consultants, reviewers, and policy makers. It is written such that both experts and beginners will find the information highly useful and applicable.

Nanotechnology in Dermatology

by Adnan Nasir

Author	: Adnan Nasir
Publisher	: Springer Science & Business Media
Total Pages	: 299
Release	: 2012-12-02
Genre	: Medical
ISBN	: 1461450349

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Nanotechnology in Dermatology is the first book of its kind to address all of the important and rapidly growing aspects of nanotechnology as it relates to dermatology. In the last few years there has been an explosion in research and development for products and devices related to nanotechnology, including numerous applications for consumers, physicians, patients, and industry. Applications are underway in medicine and dermatology for the early detection, diagnosis, and targeted therapy of disease, and nanodesigned materials and devices are expected to be faster, smaller, more powerful, more efficient, and more versatile than their traditional counterparts. Written by experts working in this exciting field, Nanotechnology in Dermatology specifically addresses nanotechnology in consumer skin care products, in the diagnosis of skin disease, in the treatment of skin disease, and the overall safety of nanotechnology. The book also discusses future trends of this ever-growing and changing field, providing dermatologists, pharmaceutical companies, and consumer cosmetics companies with a clear understanding of the advantages and challenges of nanotechnology today.

Nanotechnology Based Approaches for Tuberculosis Treatment

by Prashant Kesharwani

Author	: Prashant Kesharwani
Publisher	: Academic Press
Total Pages	: 286
Release	: 2020-06-10
Genre	: Medical
ISBN	: 0128226110

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Nanotechnology Based Approaches for Tuberculosis Treatment discusses multiple nanotechnology-based approaches that may help overcome persisting limitations of conventional and traditional treatments. The book summarizes the types of nano drugs, their synthesis, formulation, characterization and applications, along with the most important administration routes. It also explores recent advances and achievements regarding therapeutic efficacy and provides possible future applications in this field. It will be a useful resource for investigators, pharmaceutical researchers, innovators and scientists working on technology advancements in the areas of targeted therapies, nano scale imaging systems, and diagnostic modalities in tuberculosis. - Addresses the gap between nanomedicine late discovery and early development of tuberculosis therapeutics - Explores tuberculosis nanomedicine standardization and characterization with newly developed treatment, diagnostic and treatment monitoring modalities - Covers the field thoroughly, from the pathogenesis of tuberculosis and multi-drug resistant mycobacterium tuberculosis, to treatment approaches using nanotechnology and different nanocarriers

Nanotechnology in Plant Growth Promotion and Protection

by Avinash P. Ingle

Author	: Avinash P. Ingle
Publisher	: John Wiley & Sons
Total Pages	: 378
Release	: 2021-08-16
Genre	: Science
ISBN	: 1119745853

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Discover the role of nanotechnology in promoting plant growth and protection through the management of microbial pathogens In Nanotechnology in Plant Growth Promotion and Protection, distinguished researcher and author Dr. Avinash P. Ingle delivers a rigorous and insightful collection of some of the latest developments in nanotechnology particularly related to plant growth promotion and protection. The book focuses broadly on the role played by nanotechnology in growth promotion of plants and their protection through the management of different microbial pathogens. You’ll learn about a wide variety of topics, including the role of nanomaterials in sustainable agriculture, how nano-fertilizers behave as soil feed, and the dual role of nanoparticles in plant growth promotion and phytopathogen management. You’ll also discover why nanotechnology has the potential to revolutionize the current agricultural landscape through the development of nano-based products, like plant growth promoters, nano-fertilizers, nano-pesticides, and nano-insecticides. Find out why nano-based products promise to be a cost-effective, economically viable, and eco-friendly approach to tackling some of the most intractable problems in agriculture today. You’ll also benefit from the inclusion of: A thorough introduction to the prospects and impacts of using nanotechnology to promote the growth of plants and control plant diseases An exploration of the effects of titanium dioxide nanomaterials on plant growth and the emerging applications of zinc-based nanoparticles in plant growth promotion Practical discussions of nano-fertilizer in enhancing the production potentials of crops and the potential applications of nanotechnology in plant nutrition and protection for sustainable agriculture A concise treatment of nanotechnology in seed science and soil feed Toxicological concerns of nanomaterials used in agriculture Perfect for undergraduate, graduate, and research students of nanotechnology, agriculture, plant science, plant physiology, and crops, Nanotechnology in Plant Growth Promotion and Protection will also earn a place in the libraries of professors and researchers in these areas, as well as regulators and policymakers.

Nanoparticulate Vaccine Delivery Systems

by Martin J. D'Souza

Author	: Martin J. D'Souza
Publisher	: CRC Press
Total Pages	: 239
Release	: 2015-06-01
Genre	: Medical
ISBN	: 9814613312

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Recent years have seen the development of novel technologies that use nanoparticles and microparticles to deliver vaccines by the oral and microneedle-based transdermal route of administration. These new technologies enable the formulation of vaccine particles containing vaccine antigens, without loss of their biological activity during the formula

Nanotechnology in Agriculture and Food Science

by Monique A. V. Axelos

Author	: Monique A. V. Axelos
Publisher	: John Wiley & Sons
Total Pages	: 422
Release	: 2017-06-19
Genre	: Technology & Engineering
ISBN	: 3527339892

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A comprehensive overview of the current state of this highly relevant topic. An interdisciplinary team of researchers reports on the opportunities and challenges of nanotechnology in the agriculture and food sector, highlighting the scientific, technical, regulatory, safety, and societal impacts. They also discuss the perspectives for the future, and provide insights into ways of assuring safety so as to obtain confidence for the consumer, as well as an overview of the innovations and applications. Essential reading for materials and agricultural scientists, food chemists and technologists, as well as toxicologists and ecotoxicologists.