It looks at the experience of a number of countries which have tried reforming their regimes and softening prohibition, exploring the kinds of changes or penalties for use for possession: including depenalization, decriminalization, medical control, and different types of legalization. It evaluates such changes and draws on them to assess the effects on levels and patterns of use, on the market, and on adverse consequences of prohibition. For policymakers willing to look outside the box of the global prohibition regime, the book examines the options and possibilities for a country or group of countries to bring about change in, or opt out of, the global control system. Throughout, the book examines cannabis within a global frame, and provides in accessible form information which anyone considering reform will need in order to make decisions on cannabis policy (much of which is new or has not been readily available).