Sexuality is a fundamental component of human psychological experience, and yet it remains relatively underrepresented in the history of the psychological sciences. The APA Handbook on Sexuality and Psychology marks a turning point in the status of sexuality within the discipline of psychology. This comprehensive, two-volume handbook provides an overarching review of current empirical research on sexuality and a synthesis of the dominant theoretical perspectives that have guided both research and clinical practice. An organizing current throughout the volume is the integration of individual experience and social/cultural context across every domain of sexuality. This dual emphasis on person and context is reflected in the structure of the handbook itself. Volume 1 presents foundational information on the history, theoretical and methodological development and current practices in the field, and then moves on to address foundational aspects of sexuality, including desire, orientation, behavior and practices, individual lifespan development, and biological substrates. Volume 2 broadens the analytical frame to emphasize the core contextual factors known to influence the development, expression and interpretation of sexuality and its expression in and through all of the key social institutions of our society, including marginalized populations, education, sexual rights and communities, globalization, religion and the media. The APA Handbook on Sexuality and Psychology will become a defining resource of this increasingly central topic across the sub-disciplines of psychology.