The Origin of the Virus

The Origin of the Virus
Author: Paolo Barnard
Publisher:
Total Pages: 0
Release: 2021-09-30
Genre:
ISBN: 9781854571069

Ground-breaking, evidence-based book asks how many lives were lost because of Chinas negligence about lab-leaked SARS-CoV-2. In a disturbing reconstruction of events by two of the most reputable scientists in the world, a new book reveals for the first time how Chinese authorities and elite Wuhan scientists knew about SARS-CoV-2s menacing biological features from the start but remain silent to this day. In The Origin of the Virus (Clinical Press) Dr Steven Quay and Prof Angus Dalgleish, working with Italian reporter Paolo Barnard, show how China engaged in lies, omissions and obfuscations to cover up the laboratory origin of the virus. Had they immediately alerted the international community and policymakers of the extremely pathogenic molecular machinery present in SARS-CoV-2's genome, very large numbers of lives may have been spared, argue Quay, Dalgleish and Barnard. The authors provide a shocking account of the extreme experiments that led to the outbreak of the worst pandemic since the 1918 Spanish influenza. They broaden the censure to explain why some American and British scientists thwarted a proper investigation of the origin of COVID-19. Despite its impeccable scientific grounding the book is both a readable and gripping account that, for the first time, allows the public to partake in what lies at the heart of the many scandals surrounding the birth of the most deadly virus in modern times.

Origin and Evolution of Viruses

Origin and Evolution of Viruses
Author: Esteban Domingo
Publisher: Elsevier
Total Pages: 573
Release: 2008-06-23
Genre: Science
ISBN: 0080564968

New viral diseases are emerging continuously. Viruses adapt to new environments at astounding rates. Genetic variability of viruses jeopardizes vaccine efficacy. For many viruses mutants resistant to antiviral agents or host immune responses arise readily, for example, with HIV and influenza. These variations are all of utmost importance for human and animal health as they have prevented us from controlling these epidemic pathogens. This book focuses on the mechanisms that viruses use to evolve, survive and cause disease in their hosts. Covering human, animal, plant and bacterial viruses, it provides both the basic foundations for the evolutionary dynamics of viruses and specific examples of emerging diseases. - NEW - methods to establish relationships among viruses and the mechanisms that affect virus evolution - UNIQUE - combines theoretical concepts in evolution with detailed analyses of the evolution of important virus groups - SPECIFIC - Bacterial, plant, animal and human viruses are compared regarding their interation with their hosts

The Major Transitions in Evolution

The Major Transitions in Evolution
Author: John Maynard Smith
Publisher: Oxford University Press
Total Pages: 361
Release: 1997-10-30
Genre: Nature
ISBN: 019850294X

During evolution there have been several major changes in the way genetic information is organized and transmitted from one generation to the next. These transitions include the origin of life itself, the first eukaryotic cells, reproduction by sexual means, the appearance of multicellular plants and animals, the emergence of cooperation and of animal societies. This is the first book to discuss all these major transitions and their implications for our understanding of evolution.Clearly written and illustrated with many original diagrams, this book will be welcomed by students and researchers in the fields of evolutionary biology, ecology, and genetics.

Viral

Viral
Author: Matt Ridley
Publisher: HarperCollins
Total Pages: 448
Release: 2022-06-28
Genre: Medical
ISBN: 0063273608

"Chan and Ridley write with an urgency...that inspires gripping depictions of what viruses are, how infectious-disease laboratories work and wonderfully lucid descriptions of bats. . . . They powerfully recount how dangerous pathogens can both leak from a lab and emerge in nature." (New York Times Book Review) Understanding how Covid-19 started is crucial for the future of humankind. Viral is the most incisive and authoritative book about the search for the source of the virus. A new virus descended on the human species in 2019 wreaking unprecedented havoc. Finding out where it came from and how it first jumped into people is an urgent priority, but early expectations that this would prove an easy question to answer have been dashed. Nearly two years into the pandemic, the crucial mystery of the origin of SARS-CoV-2 is not only unresolved but has deepened. In this uniquely insightful book, a scientist and a writer join forces to try to get to the bottom of how a virus whose closest relations live in bats in subtropical southern China somehow managed to begin spreading among people more than 1,500 kilometres away in the city of Wuhan. They grapple with the baffling fact that the virus left none of the expected traces that such outbreaks usually create: no infected market animals or wildlife, no chains of early cases in travellers to the city, no smouldering epidemic in a rural area, no rapid adaptation of the virus to its new host—human beings. To try to solve this pressing mystery, Viral delves deep into the events of 2019 leading up to 2021, the details of what went on in animal markets and virology laboratories, the records and data hidden from sight within archived Chinese theses and websites, and the clues that can be coaxed from the very text of the virus’s own genetic code. The result is a gripping detective story that takes the reader deeper and deeper into a metaphorical cave of mystery. One by one the authors explore promising tunnels only to show that they are blind alleys, until, miles beneath the surface, they find themselves tantalisingly close to a shaft that leads to the light.

Understanding Viruses

Understanding Viruses
Author: Teri Shors
Publisher: Jones & Bartlett Learning
Total Pages: 676
Release: 2009
Genre: Medical
ISBN: 9780763729325

"Combining the molecular, clinical, and historical aspects of virology, Understanding Viruses is a textbook for the modern undergraduate virology course. The text provides an introduction to human viral diseases. Additional chapters on viral diseases of animals; the history of clinical trials, gene therapy, and xenotransplantation; prions and viroids; plant viruses; and bacteriophages add to the coverage."--Jacket.

Don't Tell the Boss!

Don't Tell the Boss!
Author: Dmitry Chernov
Publisher: Springer Nature
Total Pages: 493
Release: 2023-01-20
Genre: Business & Economics
ISBN: 3031052064

After a major disaster, when investigators are piecing together the story of what happened, a striking fact often emerges: before disaster struck, some people in the organization involved were aware of dangerous conditions that had the potential to escalate to a critical level. But for a variety of reasons, this crucial information did not reach decision-makers. So, the organization moved ever closer to catastrophe, effectively unaware of the possible threat—despite the fact that some of its employees could see it coming. What is the problem with communication about risk in an organization, and why does this problem exist? What stops people in organizations or project teams from freely reporting and discussing critical risks? This book seeks to answer these questions, starting from a deep analysis of 20 disasters where the concealment of risks played a major part. These case studies are drawn from around the world and span a range of industries: civil nuclear power, coal, oil and gas production, hydropower energy, metals and mining, space exploration, transport, finance, retail manufacturing and even the response of governments to wars, famines and epidemics. Together, case studies give an insight into why people hesitate to report risks—and even when they do, why their superiors often prefer to ignore the news. The book reviews existing research on the challenges of voice and silence in organizations. This helps to explain more generally why people dread passing on bad news to others—and why in the workplace they prefer to keep quiet about unpleasant facts or potential risks when they are talking to superiors and colleagues. The discussion section of the book includes important examples of concealment within the Chinese state hierarchy as well as by leading epidemiologists and governments in the West during the novel coronavirus outbreak in Wuhan in 2019-2020. The full picture of the very early stage of the COVID-19 pandemic remains unclear, and further research is obviously needed to better understand what motivated some municipal, provincial and national officials in China as well as Western counterparts to obfuscate facts in their internal communications about many issues associated with the outbreak.

Animal-Origin Viral Zoonoses

Animal-Origin Viral Zoonoses
Author: Yashpal Singh Malik
Publisher: Springer Nature
Total Pages: 386
Release: 2020-09-23
Genre: Medical
ISBN: 9811526516

This book is the second volume in the series Livestock Diseases and Management, and reviews the importance and implications of animal origin viral zoonoses. It also highlights the specific etiology and epidemiology of these viral infections and discusses their various biological and mechanical transmission mechanisms. Further, the book reviews various measures for controlling viral zoonoses and examines novel therapeutic and prophylactic strategies. Discussing recent studies on the pathogenesis and host immune response to these infections, it underscores the importance of using vaccines against these viral diseases to reduce the risk of them being transmitted to humans.Lastly, it describes in detail the challenges posed by these viral infections and our readiness to face them.

Prebiotic Chemistry and the Origin of Life

Prebiotic Chemistry and the Origin of Life
Author: Anna Neubeck
Publisher: Springer Nature
Total Pages: 296
Release: 2022-01-03
Genre: Science
ISBN: 3030810399

This book presents an overview of current views on the origin of life and its earliest evolution. Each chapter describes key processes, environments and transition on the long road from geochemistry and astrochemistry to biochemistry and finally to the ancestors of today ́s organisms. This book combines the bottom-up and the top-down approaches to life including the origin of key chemical and structural features of living cells and the nature of abiotic factors that shaped these features in primordial environments. The book provides an overview of the topic as well as its state of the art for graduate students and newcomers to the field. It also serves as a reference for researchers in origins of life on Earth and beyond.

Sessional Papers

Sessional Papers
Author: Great Britain. Parliament. House of Commons
Publisher:
Total Pages: 996
Release: 1907
Genre: Great Britain
ISBN: